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Positive Long-Term Data For BENLYSTA (formerly LYMPHOSTAT-B(R)) In Patients With Active Lupus
Human Genome Sciences (HGS) has reported continuation data from a Phase II study of BENLYSTA™ (belimumab, formerly LymphoStat-B®) showing sustained improvement in patients with active systemic lupus after four years of treatment. The data was presented at the EULAR 2009 scientific meeting in Copenhagen, Denmark.

Oregon House Passes Preemptive Health Reform Bills
The Oregon House of Representatives passed two health reform bills that a leading Democratic lawmakers says will help Oregon "fit into whatever happens on the national scale," the Portland Oregonian reports. One bill would tax insurers and hospitals more than $300 million over two years to provide coverage to an additional 115,000 Oregonians. These funds would "leverage nearly $1 billion in federal Medicaid matching money." The second measure would create an Oregon Health Authority to replace an existing Department of Human Services, but with a broader mandate to track health care claims data and harness consolidated purchasing power to "pressure insurers and hospitals to use evidence based care." State officials say the measure "would create an estimated 3,600 high-paying jobs in hospitals, medical clinics and other areas" (Graves, 6/8).
News of the day
Efforts To 'Fix' Medicare Payments At Center Of Reform
The Wall Street Journal reports: "A plan to end a program that would cut government payments to doctors is emerging as the flash point in the debate over whether President Barack Obama"s effort to overhaul the health system would increase the federal budget deficit. The proposal was crucial to winning support from the politically powerful American Medical Association -- but it has also made it tougher to argue that the health overhaul would pay for itself. ... Health and Human Services Secretary Kathleen Sebelius, appearing on NBC"s "Meet the Press," said costs associated with the legislation could be reduced significantly if lawmakers included the administration"s recommendation to bolster the power of the Medicare Payment Advisory Commission, or MedPAC, to set Medicare payment policies.

Cardiovascular

New Interventional Pain Management Guidelines Released By The American Society Of Interventional Pain Physicians

The American Society of Interventional Pain Physicians (ASIPP) announced they have released the 2009 updated Interventional Pain Management (IPM) guidelines.

One Force Behind The MYC Oncogene In Many Cancers Uncovered By Fox Chase Researchers

DLX5, a gene crucial for embryonic development, promotes cancer by activating the expression of the known oncogene, MYC, according to researchers from Fox Chase Cancer Center. Since the DLX5 gene is inactive in normal adults, it may be an ideal target for future anti-cancer drugs, they reason. Their findings are published in the July 31 edition of the Journal of Biological Chemistry, available online now.

HIV/AIDS Vaccine Coalition Urges Continued Funding For Research Amid Economic Crisis

A recently released AIDS Vaccine Advocacy Coalition report says that although there has been a renewed focus on discovery, innovation and basic science in vaccine research, action is needed to ensure that research funding continues during the economic downturn, VOA News reports. AVAC executive director Mitchell Warren said the report is "about putting all the pieces together ... not just the search for an AIDS vaccine, but in fact the entire HIV prevention response." He added, "[T]he good news is we have some new pieces of the puzzle, and we"re expecting additional new pieces of understanding through research this year." Warren said that AVAC believes HIV/AIDS vaccine research is in "one of the most exciting times," with "new energy, new commitment to unlocking some of the basic scientific roadblocks that have impeded our ability to find a vaccine." For example, a study released earlier this week examined efforts to produce a vaccine through genetic transfer. Regarding the study, Warren said, "It doesn"t mean we have an AIDS vaccine, but it means we have an entirely new approach to trying to deliver protection." Warren said that the field of HIV/AIDS vaccine research has shown a renewed commitment since Merck canceled its vaccine trial in 2007. According to Warren, the new AVAC report examines knowledge gained from the Merck study, which has provided "an unimaginable amount of information." Meanwhile, the effect of the economic crisis on research funding is concerning, Warren said, adding, "I believe that every dollar spent is going to be held up to a greater scrutiny as budgets tighten and as funders have to re-examine their priorities." According to Warren, without renewed funding commitments, "we will not only incur a much greater public health catastrophe, but I would argue that the economic catastrophes to come, if we don"t respond aggressively to HIV, will actually have repercussions that will ... make the economic crisis pale in comparison" (DeCapua, VOA News, 5/18).

Shanghai To Relax One-Child Policy As China Faces Aging Population, Shrinking Work Force

Nearly three decades after China implemented its one-child policy, the city of Shanghai is planning to encourage young couples to have a second child in an effort to address the country"s aging population and shrinking work force, the New York Times reports. The city"s plan is the most public effort made by the government to counteract a program that is "considered both a tremendous success and a terrible failure," the Times reports. The policy has managed to keep population growth under control but also has led to forced abortions, according to the Times.The country is not abandoning the one-child policy, which applies mostly to residents in urban areas. Rather, the government is allowing more exceptions to the rule, with Shanghai -- where about 22% of its 20 million residents are older than age 60 -- leading the effort. China as a whole faces a similar problem seen in Shanghai, the Times reports. About 8% of the country"s population was older than age 65 in 2006. That figure is expected to increase threefold by 2050 to about 322 million people, or nearly 25% of the population, according to the United Nations.In Friday"s issue of China Daily, Xie Lingli, director of the Shanghai Population and Family Planning Commission, was quoted as saying, "We advocate eligible couples to have two kids because it can help reduce the proportion of the aging people and alleviate a work force shortage in the future." City officials plan to visit homes, pass out leaflets, and offer counseling and financial incentives, the Times reports. Current exceptions to the one-child policy are in place for ethnic minorities and rural residents, who can have a second child if the first child is a girl. Couples made up of two parents who have no siblings have always been allowed to have a second child and are now being encouraged to do so (Barboza, New York Times, 7/24).

FDA Warns Consumers Not To Use Body Building Products Marketed As Containing Steroids Or Steroid-Like Substances

The U.S. Food and Drug Administration issued a Public Health Advisory (PHA) warning consumers to stop using body building products that are represented as containing steroids or steroid-like substances. Many of these products are marketed as dietary supplements.

House Democrats Hope To Forge Deal On Package, Wait For Score

As they worked to move health care reform legislation through the Energy and Commerce Committee, House Democrats said they were close to a compromise with fiscally conservative Democrats, a group that so far has been a roadblock, The Hill reports.

Jury Rules For Florida Hospital That Deported Brain-Damaged Immigrant Patient

"In a benchmark case dealing with the obligations of hospitals toward uninsured illegal immigrants, a jury in Stuart, Fla., decided Monday that Martin Memorial Medical Center did not act unreasonably when it chartered a plane and repatriated a severely brain-injured Guatemalan patient against the will of his guardian," The New York Times reports.

New York Times Profiles Afghani Maternal Health Advocate

The New York Times profiles Pashtoon Azfar, the director of Afghanistan"s Institute of Health Sciences, who works for a nonprofit group from Johns Hopkins University that focuses on women and children"s health, and "also manages to serve as president of the Afghan Midwives Association." Azfar was the "star" of a recent Capitol Hill briefing about maternal health in Afghanistan.

Cannabis Science Receives FDA Industry Guidelines For Mapping Out Its Initial Drugs Offerings For FDA Submission And Testing

Cannabis Science Inc. (OTCBB: CBIS), an emerging pharmaceutical cannabis company, is pleased to report that the FDA has provided the Company with documentation to assist the Company to review and plan its initial applications to get its first drug into formal testing.

Illinois Counties Facing Increases In STDs Among Teenagers; Bill Aims To Reduce Rates

Illinois health officials contend that images seen in the media, social influences, and a lack of "frank" discussion on STDs in schools, among other issues, might be contributing to increases in STD rates across the state, the State Journal-Register reports. "According to recently released data, new cases of chlamydia in Illinois reached an all-time high statewide in 2008 - 59,169 - while the number of gonorrhea cases outside Chicago has been rising in recent years and totaled 10,165 in 2008," the Journal-Register reports. In addition, about 35,000 state residents have HIV/AIDS, the article states. Charlie Rabins, chief of the STD program at the Illinois Department of Public Health, said a bill (SB 212) currently awaiting Gov. Pat Quinn"s (D) approval might help reduce STD rates. The bill "would allow what is called "expedited partner therapy," in which medical professionals who treat patients for gonorrhea or chlamydia can give those patients single-dose antibiotics to pass on to sexual partners without first examining the partners," according to the Journal-Register (Olsen, 7/27).

Ventana\'s Promising New Anti-Obesity Patent

Ventana Biotech Inc ("Ventana")(PINK SHEETS:VNTA), a biotechnology company that is developing a appetite-suppressing chewing gum, released detailed information about its innovative Anti-Obesity Chewing Gum.

New Survey: Health Care Leaders Say Need For Reform Is Urgent; Broadly Support Public Health Care Option, Provider Payment Reform

By a wide margin, health care leaders believe that individuals should have a choice of public and private health plans, and strongly support other central components of health reform such as innovative provider payment reform and a national insurance health exchange with strong standard-setting authority. In addition, two-thirds (68%) of opinion leaders feel it is urgent to enact comprehensive health care reform this year, according to the latest Commonwealth Fund/Modern Healthcare Health Care Opinion Leaders Survey.

CytRx Drug Candidate INNO-206 Results In Ovarian Tumor Shrinkage In Animal Trials

CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, announced that results demonstrating that its cancer drug candidate INNO-206 caused statistically significant tumor shrinkage in an animal model of ovarian cancer have been accepted for publication in the peer-reviewed journal Investigational New Drugs. The manuscript based on this animal trial, "INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model," was made available ahead of journal printing in electronic format in the January 8, 2009 on-line issue of Investigational New Drugs.

Parents Needed To Help Curb Teenage Births Among Hispanics, Group Says

A coalition of Hispanic organizations on Tuesday urged parents of Hispanic teenagers to talk with their children about sex to curb the high teenage birth rate among the group, the McClatchy/Miami Herald reports. Hispanics are predicted to make up 25% of the teenage population nationwide by 2025 and efforts to curb their teen pregnancy rate is key to reducing unwanted pregnancies among all teenagers, according to the McClatchy/Herald. More than half of Hispanic teenage girls will become pregnant before age 20 -- nearly twice the national average and the highest of any ethnic or racial group in the U.S., according to coalition, which includes MANA, a national Hispanic women"s organization. Ana Sol Gutierrez, a member of the Maryland House of Delegates and a participant in the coalition, said the higher pregnancy rates among Hispanic teenagers can be attributed in part to a "different mind-set" among the group that embraces motherhood even at a young age. She said the key to reducing unplanned teenage pregnancies among Hispanics is to educate them about choosing "when and how" to become parents, while still embracing maternity. The National Campaign To Prevent Teen and Unplanned Pregnancy surveyed more than 1,600 Hispanic teenagers and adults nationwide and found that 76% of teens said their parents most influenced their decisions about sex but that most parents said they did not know how to have such a conversation with their children. The finding was particularly evident among parents who only speak Spanish. Ruthie Flores, a co-author of the study, said the solution is culturally appropriate education (Chung, McClatchy/Miami Herald, 5/19).

Prostate Cancer Screening And Trust Of Physician Evaluated

Trusted health care s and continuity of care may help reduce the risk of prostate cancer deaths in African-American men, according to a study published in the current issue of the journal Cancer. James Mohler, MD, Chair of the Department of Urology at Roswell Park Cancer Institute (RPCI), and William R. Carpenter, PhD, Department of Health Policy and Management at the University of North Carolina, are lead investigators.

National Review Of The Independent Reviewing Officer Service In Wales

The Care and Social Services Inspectorate Wales (CSSIW) published its report on the review of Independent Reviewing Officer (IRO) service in Wales.

Men And Women See Things Differently

Sex differences in how the brain processes visual information could be a legacy of our hunter-gather past. This is the conclusion of a paper published online today, 30th July 2009, in the British Journal of Psychology.

Pseudoephedrine Decision Demonstrates Confidence In Community Pharmacy

The NPA is pleased by today"s decision from the MHRA to keep pseudoephedrine a P medicine and have no doubt that community pharmacies will continue to ensure pseudoephedrine is sold in line with MHRA guidance.

Three Organizations Form Alliance To Address Global Malnutrition

"Three internationally known organizations based in St. Louis - the Donald Danforth Plant Science Center, the Washington University School of Medicine and St. Louis Children"s Hospital" - have entered into a partnership, known as the Global Harvest Alliance (GHA), which aims to "create inexpensive, nutritionally complete food to help the world"s hungry and undernourished," the AP/Google.com reports. Alliance researchers will focus on several of the most successful approaches used to combat malnutrition and attempt to further enrich foods already used to fight it. "In addition, the alliance aims to help testing and distribution of crops genetically modified to boost nutritional content. They hope to provide the crops cheaply to farmers to produce more nutritious foods," writes the AP/Google.com (Taylor, 7/29).

Latin America Accounts For Two-Thirds Of All Confirmed H1N1 Deaths

Health officials are growing increasingly concerned over the impact the H1N1 (swine) flu is having on populations living in Latin America, a region "which accounts for around two-thirds of the 816 confirmed deaths so far from the disease," the AFP/channelnewsasia.com reports. "The outlook is especially unsettling for the estimated 380 million people grappling with winter in South America, where the A(H1N1) virus is speedily propagating," the news service writes. The article examines the number of H1N1 cases and deaths across countries and how government officials are working to prevent the spread of the virus (7/29).

Shutting Down Health Care Fraud; Increasing Transparency

U.S. Senator Mel Martinez (R-FL) joined with U.S. Senator Amy Klobuchar (D-MN) on an effort to require all Medicare and Medicaid provider payments to be made through direct deposit at federally-insured banking institutions. If signed into law, this measure will make it easier to track providers engaged in fraud thereby dramatically reducing the estimated loss of more than $60 billion every year.

Sixth International Congress On Peer Review And Biomedical Publication

When

Indiana University Student Outreach Clinic To Provide Free Health Care To The Uninsured

People without health insurance will have another avenue for medical care beginning Aug. 1 when student volunteers at the Indiana University School of Medicine open the IU Student Outreach Clinic in a near eastside Indianapolis neighborhood.

Employing People With Autism Could Save The UK Economy Billions Each Year

A unique event to discuss Autism and employment was held at Goldsmiths, University of London this week. For the first time charities, researchers, business and government were brought together to look at how people with Autism, and related disorders, can be supported effectively into employment.

From Molecular Physiology To Therapeutic Applications Of Stem Cells

Stem cell research promises remedies to many devastating diseases that are currently incurable, ranging from diabetes and Parkinson"s disease to paralysis. Totipotent embryonic stem cells have great potential for generating a wide range of different human cells that can be used to restore malfunctioning or damaged cells and tissues in patients. Recent studies have shown that pluripotent stem cells derived from adult bone marrow, the umbilical cord and the placenta could also be induced to differentiate into a variety of different tissues. In this issue, we have invited several scientists in China to summarize their pioneering works in the stem cell research field.

Painting Clearer Picture Of Biological Processes Using \'Microfluidic Palette\'

The masterpieces that spring from the talents of Rembrandt, Van Gogh and other artists often begin with the creation of a gradient of colors on a palette. In a similar manner, researchers at the National Institute of Standards and Technology (NIST) have created an innovative device called the "microfluidic palette" to produce multiple, steady-state chemical gradients - gradual changes in concentration across an area - in a miniature chamber about the diameter of a pinhead. The tool can be used to study the complex biological mechanisms in cells responsible for cancer metastasis, wound healing, biofilm formation and other fluid-related processes.

If Bipolar Disorder Is Over-Diagnosed, What Are The Actual Diagnoses?

A year ago, a study by Rhode Island Hospital and Brown University researchers reported that fewer than half the patients previously diagnosed with bipolar disorder received an actual diagnosis of bipolar disorder after using a comprehensive, psychiatric diagnostic interview tool -- the Structured Clinical Interview for DSM-IV (SCID). In this follow-up study, the researchers have determined the actual diagnoses of those patients. Their study is published in the July 28 ahead of print online edition of The Journal of Clinical Psychiatry.

Ambulance Phone Triage System Misses More Than 50% Of Stroke Patients

[Is ambulance telephone triage using advanced medical priority despatch protocols able to identify patients with acute stroke correctly? Emerg Med J 2009; 26: 442-5]

Glutaric Aciduria Type I: Therapy Should Extend Beyond Childhood

By systematically analysing MRI changes occuring in the brains of children with the metabolic disease glutaric aciduria type I researchers at Heidelberg University Hospital have succeeded for the first time in demonstrating reversible and permanent brain damage as well as elucidating its temporal evolution.

Women Show More Pronounced Health Benefits From Physical Activity

Many experimental studies have found that physical exercise can improve cholesterol levels and subsequently decrease the risks of cardiovascular disease; however, few of these studies have included enough participant diversity to provide ethnic breakdowns. Now, a long-term study of over 8,700 middle-aged men and women provides race- and gender- specific data on the cholesterol effects of physical activity, with the interesting result that women, particularly African-American women, experience greater benefits as a result of exercise than men.

Immune Responses To Flu Vaccine Are Diminished In Lupus Patients

Patients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of infection, due to both disturbances in their immune responses and treatment with immunosuppressive drugs. Because morbidity and mortality related to influenza are increased in immunocompromised patients, it is recommended that patients with SLE get annual flu shots, which are safe and do not increase disease activity. Both antibody and cell-mediated responses are involved in the immune response to influenza; in SLE, antibody responses to the vaccine are diminished, but it is not known if the same effect is seen in cell-mediated responses. A new study was the first to examine cell-mediated responses in SLE patients prior to and following influenza vaccination. The study was published in the August issue of Arthritis & Rheumatism .

Sciele Pharma And Plethora Solutions Announce Positive Results Of Final Phase III Pivotal Trial For PSD502 For Premature Ejaculation

Sciele Pharma Inc., a Shionogi Company, and Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE), announced that a second and final Phase III double-blind, placebo-controlled study of PSD502 for the treatment of premature ejaculation ("PE") has met all co-primary endpoints of Intra-vaginal Ejaculation Latency Time ("IELT"), Index of Premature Ejaculation ("IPE," Ejaculatory Control, Sexual Satisfaction and Distress domains).

Smokefree Innotec, Inc. Addresses FDA Concerns About Electronic Cigarettes

Smokefree Innotec, Inc. (Pink Sheets: SFIO) issued a statement referring to articles in USA Today and The New York Times of Wednesday, July 22, and Thursday, July 23rd, regarding the FDA taking aim at electronic cigarettes. The national dailies stated that tests show that certain e-cigarettes contain "known carcinogens and toxic chemicals," including diethylene-glycol (an ingredient used in antifreeze, printing ink, brake fluid and glue) and nitrosamine (which is used in rubber products, the tobacco industry, and - less concentrated - in beer and fish-products).

Comfrey Root Extract Ointment Relieves Back Pain Fast

[Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double blind randomised placebo controlled multicentre trial Online First Br J Sports Med 2009; doi: 10.1136/bjsm.2009.058677]

Low Levels Of Contamination Found In Ready-to-eat Speciality Meats Sold In UK

A new report published highlights that 99% of ready-to-eat speciality meats sold in the UK are safe to eat. However the study also reveals that a very small proportion of the meats contained Salmonella or unsafe levels of Listeria monocytogenes.

WellPoint Announces Decision To Cover H1N1 Vaccine Administration

WellPoint, Inc. (NYSE: WLP) announced today that it will offer coverage for the administration of the H1N1 (swine flu) vaccine when it becomes commercially available to the general public. The vaccine administration will be covered for members whose benefit plans provide coverage for vaccines.

Thousands Of New Mexicans Could Lose Private Insurance, Study Shows

An estimated 428,000 residents in New Mexico could lose their private, employer-based coverage if Congress passes a House health reform bill, according to state-specific analysis of The American Affordable Health Choices Act of 2009 released this week by The Heritage Foundation.

Action Needed Now To Stop NHS Wales Becoming Unsafe For Staff And Patients - Says British Medical Association Cymru Wales

Doctors" leaders are warning that unless urgent action is taken to plug the gap in the shortage of middle grade doctors, the NHS in Wales could become unsafe both for staff and patients.

British Medical Association Comment On Announcement On NHS Treatment Centres

The Department of Health announced that the terms offered to independent providers of treatment centres in the NHS in England will in future be more similar to those offered to NHS providers.

New Training And Education Programme Introduced For The Scientific Workforce In Genetics, UK

A new education programme has been developed to provide enhanced training in genetic technologies and clinical applications for healthcare scientists working in laboratory genetics, Health Minister Ann Keen announced.

What Is Alzheimer\'s Disease? What Causes Alzheimer\'s Disease?

Alzheimer"s disease is a progressive neurologic disease of the brain leading to the irreversible loss of neurons and the loss of intellectual abilities, including memory and reasoning, which become severe enough to impede social or occupational functioning. Alzheimer"s disease is also known as simply Alzheimer"s, and Senile Dementia of the Alzheimer Type (SDAT) .

Educate, Collaborate, Share And Network On HIMSS Clinical Decision Support Wiki

New wiki supports collaboration and accelerates progress on using clinical decision support for healthcare performance improvement

Insurers Struggle In Downturn As Senators Consider Adding New Tax

"Earnings from the nation"s big health insurers show signs of a new uptick in medical costs related to the recession: As unemployment rises, people who have lost their jobs or are fearful of losing them are rushing to see doctors to get medical tests before their benefits expire," the Wall Street Journal reports. WellPoint, the nation"s largest insurer by volume, reported a 7.6 percent dip in profits and the loss of 338,000 members in the second quarter, further illuminating the trend. Other insurers have experienced similar patterns in which policyholders are seeking more - and more expensive - health services.

Use Science To Convince Teens A Sober Prom Is Better, American Association for the Advancement of Science Says

This is the time of year when even teens who have never tried a drop of alcohol may be tempted. Middle and high school proms and graduation are big events and there will be multiple parties to attend and a wide array of opportunities for alcohol to be served.

Rush University Commencement Ceremony, June 13 At The UIC Pavilion

Rush University will award 536 baccalaureate and graduate degrees at its 37th commencement ceremony on Saturday, June 13, at 1:45 p.m. at the UIC Pavilion, 525 South Racine, Chicago.

New Strategy May Be Valid Alternative To Traditional Antibiotics

Certainly there is strength in numbers, but only if those numbers can effectively communicate with one another. Now, a new study finds that administration of a novel small molecule which effectively disrupts a key bacterial communication process protects an animal host from infection. The research, published by Cell Press in the July 31st issue of the journal Molecular Cell, may lead to more effective treatments for bacterial infection that won"t encourage growth of treatment resistant bacteria.

Physicians Can Lead Health Care Reform Through Payment And Delivery System Reforms

Physicians can and should play a leading role in achieving health care reform by working towards comprehensive reform of the way health care is paid for and delivered, helping achieve a guaranteed 1.5 percent annual savings in health care costs that would pay for covering all Americans, according to a New England Journal of Medicine Perspective piece published online.

How Resveratrol In Red Wine Works As An Effective Therapy For Life-Threatening Inflammation

Scientists from Scotland and Singapore have unraveled a mystery that has perplexed scientists since red wine was first discovered to have health benefits: how does resveratrol control inflammation? New research published in the August 2009 print issue of The FASEB Journal, not only explains resveratrol"s one-two punch on inflammation, but also show how it - or a derivative - can be used to treat potentially deadly inflammatory disease, such as appendicitis, peritonitis, and systemic sepsis.

Algebra Adds Value To Mathematical Biology Education

As mathematics continues to become an increasingly important component in undergraduate biology programs, a more comprehensive understanding of the use of algebraic models is needed by the next generation of biologists to facilitate new advances in the life sciences, according to researchers at Sweet Briar College and the Virginia Bioinformatics Institute (VBI) at Virginia Tech.

Children Capable Of Lifesaving CPR

Nine-year-olds can and should learn CPR. A study of 147 schoolchildren, published in BioMed Central"s open access journal Critical Care, has shown that, although the smallest may lack the requisite strength, the knowledge of how to perform basic life support is well retained by young children.

Unique Immunization Method Provides Insights About Protective Anti-Malaria Immune Response

In this week"s New England Journal of Medicine, scientists in Singapore, The Netherlands and France report that they have developed a novel immunization method that will induce fast and effective protection in humans against the life-threatening malaria parasite, Plasmodium falciparum, which infects 350 to 500 million people world-wide and kills over one million people each year.

Antibody Targeting Of Glioblastoma Shows Promise In Preclinical Tests, Say Lombardi Researchers

Cancer researchers at Georgetown University"s Lombardi Comprehensive Cancer Center have successfully tested a small, engineered antibody they say shuts down growth of human glioblastoma tumors in cell and animal studies. Glioblastoma is the deadliest of brain cancers; there is no effective treatment.

Shire Announces Study Results Of The Effects Of INTUNIV™ Extended Release On Secondary Measures In Children With ADHD And Oppositional Symptoms

Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced new findings on INTUNIV (guanfacine) extended release, a selective alpha-2A-agonist, at a major psychiatric meeting. This randomized placebo controlled trial met its primary objective, which was to evaluate the effects of INTUNIV on oppositional symptoms in children aged 6 to 12 years with a diagnosis of ADHD and the presence of oppositional symptoms. The data presented today on this investigational compound reviewed secondary efficacy measures from three different rating scales.

HHS Secretary Sebelius, Agriculture Secretary Vilsack Announce New Strategies To Keep America\'s Food Supply Safe

HHS Secretary Kathleen Sebelius and Agriculture Secretary Tom Vilsack announced today that prevention and partnership will guide their departments" efforts to safeguard the food Americans eat every day. Both Secretaries announced new strategies that focus on prevention and depend on working closely with growers, food processors and consumers to achieve their goals.

What Is Diphtheria? What Causes Diphtheria?

Diphtheria is a bacterial infection in the upper respiratory tract. Typically it is characterized by sore throat, swollen neck glands, high temperature and breathing difficulties. Through means of successful immunization diphtheria is now very rare in the United States and Europe. However it"s still common in countries where immunization programs are not an integral part of standard public health care. It is a potentially fatal disease with an estimated 5-10% fatality rate. In children under 5 and adults over 40 the fatality rate may sometimes reach 20%.

GlaxoSmithKline And Genmab Announce Top-line Results For Ofatumumab In Rheumatoid Arthritis

GlaxoSmithKline (GSK) and Genmab A/S (OMX: GEN) announced preliminary top-line results from a Phase III study of ofatumumab administered intravenously for the treatment of rheumatoid arthritis (RA) in patients who had an inadequate response to methotrexate. The study met the primary endpoint, ACR20 at 24 weeks, which indicates a 20 percent or greater improvement in the number of swollen and tender joints, as well as improvements in other disease-activity measures.

FDA Issues Complete Response Letter For INTUNIV™ (guanfacine) Extended Release For The Treatment Of ADHD In Children And Adolescents

Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces that it has received a Complete Response letter for INTUNIV TM (guanfacine) Extended Release from the Food and Drug Administration (FDA). This decision comes following labeling discussions with the FDA that did not result in agreement in time to meet the PDUFA date.

$940,000 In Stimulus Funds Won By UTSA Biologists To Advance Research: 2 Studies Will Focus On Food Safety And Disease Prevention

San Antonio тЂ¦ Robert Renthal, professor of biochemistry in the College of Sciences" Department of Biology at The University of Texas at San Antonio and JosУ© Lopez-Ribot, professor of microbiology in UTSA"s Department of Biology and a member of the university"s South Texas Center for Emerging Infectious Diseases, have received a combined $940,000 in stimulus funding from the National Institutes of Health to further their research over the next two years.

In Parkinson\'s Fly Model, Dementia Induced And Blocked

Parkinson"s disease is well-known for impairing movement and causing tremors, but many patients also develop other serious problems, including sleep disturbances and significant losses in cognitive function known as dementia.

Obama Issues Directive To Enact New Embryonic Stem Cell Research Rules

President Obama on Thursday issued a directive to federal agencies to begin following new NIH guidelines on federally funded embryonic stem cell research, Reuters/New York Times reports (Reuters/New York Times, 7/30). NIH announced the final guidelines earlier this month. The guidelines assess whether newly created embryonic stem cell lines can be used for federally funded research, as well as clarify how old lines will be evaluated (Daily Women"s Health Policy Report, 7/7).In March, Obama overturned President George W. Bush"s policy limiting federal funding of embryonic stem cell research. In a statement Thursday, Obama said, "I hereby direct the heads of executive departments and agencies that support and conduct stem cell research to adopt these guidelines, to the fullest extent practicable in light of legal authorities and obligations" (Reuters/New York Times, 7/30).

Blogs Comment On Ryan-DeLauro Bill, Sex Education Funding, State Reproductive Health Legislation

The following summarizes selected women"s health-related blog entries.~ "A Taxing Problem," Jessica Arons, Huffington Post blogs: The five Democrats who last week sent a letter to House Speaker Nancy Pelosi (D-Calif.) "suggesting a "common ground" solution to the abortion "roadblock" in health care reform" should be "applauded" for keeping the debate"s focus on covering the uninsured and "for being unwilling to sacrifice health care reform on the altar of abortion politics," writes Jessica Arons, director of the Women"s Health & Rights Program at the Center for American Progress. Arons adds that while the proposal, led by antiabortion-rights Rep. Tim Ryan (D-Ohio), "is in welcome contrast to the stonewalling and ultimatums coming from Rep. Bart Stupak (D-Mich.) and his allies," it is "based on a misguided and attenuated definition of government spending, and it conflicts with what Americans want and expect from health care reform." She continues that the "suggestion that a health plan might offer abortion coverage, and it might be used by someone, who might have paid a lower premium than someone else, because the government might have helped pay their premium is a horrible reason for Congress to carve out an explicit exception to a bill that is otherwise entirely silent on coverage options." Taxpayers "do not have the right to specify how their tax money should be spent," she writes, adding, "I understand why people would want to withhold their taxes from purposes they oppose, but our system does not -- nor should it -- work that way" (Arons, Huffington Post blogs, 7/30).~ "The Breakup of the Pro-Life Movement," Cristina Page, Birth Control Watch: Rep. Ryan is "in many ways a typical pro-life American" who opposes abortion rights and, "like most pro-life Americans, ... supports every effort to prevent the need for it," including contraception, Page writes. However, because of his support for contraception and sponsorship of the "Preventing Unintended Pregnancies, Reducing the Need for Abortion and Supporting Parents Act," Ryan was "banished" from the board of Democrats for Life of America, Page writes, adding that antiabortion-rights publications have "taken to qualifying his pro-life status as "allegedly" pro-life or referring to him as someone "who claims to be" pro-life." The bill, also known as the Ryan-DeLauro bill, would increase funding for contraception, and support comprehensive sex education and services for women who choose to carry unintended pregnancies to term, Page writes. She notes that the bill is supported by "many prominent pro-life individuals" and groups that support abortion rights, though "[n]ot one leading pro-life group signed onto the bill." Page writes, "Pro-life Americans favor expanding access to contraception because of the undeniable pro-life results," adding, "Unintended pregnancy is the root cause of abortion. We know when used properly, contraception works." It is "time for the disagreement over contraception to be addressed by the pro-life community at large," she writes, adding, "We will have no chance of making a real impact on unintended pregnancy and abortion rates without dramatic, informed strategies on prevention" (Page, Birth Control Watch, 7/28).~ "Senate Subcommittee: Ab-Only Out, Syringe Ban Still In; Advocates Hope for Further Changes in Conference Committee," Jodi Jacobson, RH Reality Check: The spending bill approved yesterday by the Senate Appropriations Committee "zeroes out funding" for the Community-Based Abstinence Education program, which has "for years [been] the main of support for now-discredited abstinence-only programs," Jacobson writes. The "elimination of these funds parallels similar action in the House, ... so unless amendments are proposed, accepted and passed during either the full committee vote or on the Senate floor, this bill spells "the end of abstinence-only programs as we know them," said one advocate, "at least for this year,"" Jacobson writes. The Senate version of the bill allocate

Gene Variant That Increases Ovarian Cancer Risk Discovered

By searching millions of DNA variations in the genomes of thousands of women with and without ovarian cancer, scientists have discovered a

Capps Celebrates Energy And Commerce Passage Of Comprehensive Health Insurance Reform Bill

On Friday Congresswoman Lois Capps celebrated the Energy and Commerce Committee"s passage of comprehensive health insurance reform, the America"s Affordable Health Choices Act (H.R. 3200). For the first time the Energy and Commerce Committee has passed a comprehensive health insurance reform bill, marking a historic point in the effort to lower health care costs for families and businesses, improve American"s health and wellness, and provide all Americans with access to quality, affordable health care. The measure passed by a vote of 31 to 28.

Turner Syndrome Society Of The United States Announces Ambitious Goal To Crush Ignorance Of Turner Syndrome (TS)

The Turner Syndrome Society of the United States (TSSUS) recently concluded its 22nd Annual Conference in Portland, Oregon. The conference drew more than 350 individuals, families, researchers and health care professionals to network and learn about the latest research breakthroughs benefiting women and girls with TS.

Twin Study Examines Associations Between Depression And Coronary Artery Disease

Major depression and coronary artery disease are only modestly related throughout an individual"s lifetime, but studying how the two interact over time and in twin pairs paints a more complex picture of the associations between the conditions, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals. For example, the association between coronary artery disease onset and major depression risk is much stronger over time than vice versa.

Safe For Passengers With Lung Disease To Travel By Air

Oxygen levels while flying are substantially less than at ground level. Current guidelines for in-flight oxygen levels are sufficient to support the needs of passengers with non-obstructed lung disease. According to two articles published in the Wiley-Blackwell journal, Respirology, commercial air travel appears to be safe for patients with lung disease as the current policies for the in-flight oxygen levels and availability of supplemental oxygen can adequately accommodate passenger"s needs.

Micromet Receives European Orphan Drug Designation For Treatment Of Acute Lymphoblastic Leukemia With BiTE Antibody Blinatumomab

Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases, announced that it has received Orphan Drug Designation from the European Medicines Agency (EMEA) for BiTE antibody blinatumomab (MT103) for acute lymphoblastic leukemia (ALL). Blinatumomab is a novel therapeutic antibody that activates a patient"s T cells to seek out and destroy cancer cells.

Oncothyreon Announces Presentation Of Long-term Stimuvax Data At World Conference On Lung Cancer

Oncothyreon Inc. (Nasdaq: ONTY) (TSX:ONY) (the "Company") announced that clinical data relating to long-term treatment with Stimuvax were presented at the International Association for the Study of Lung Cancer"s 13th World Conference on Lung Cancer in San Francisco on August 1, 2009. The presentation by Dr. Glenwood Goss from the Ottawa Hospital Cancer Centre, Ottawa, Ontario, involved 16 patients who received treatment with Stimuvax for between 2 and 8.2 years as part of the Phase 2b trial in patients with stage IIIb/IV non-small cell lung cancer (NSCLC).

Effectiveness Of Pelvic Floor Exercises, Digital Vaginal Palpation And Interpersonal Support On Stress Urinary Incontinence

UroToday.com - Pelvic floor muscle exercise (PFME) is most appropriate for patients with mild-to-moderate stress urinary incontinence (SUI). To obtain therapeutic efficacy, it is crucial that PFME be performed correctly and consistently. Without appropriate training; however, up to 30% of patients are not aware of how to perform PFME.

Comp. Effectiveness Promises Better, Cheaper Health Care But Critics Link It To Rationing

"Federal health agencies, seeking to hand out stimulus funds to research the effectiveness of various medical treatments, said they will include projects that look in part at the cost of drugs and other treatments. The approach -- which was unveiled in a report to Congress this week by the Agency for Healthcare Research and Quality and the National Institutes of Health, both agencies under the Department of Health and Human Services -- could provide more fodder to conservatives worried that the government might use the results of such studies to limit health care to consumers," the Wall Street Journal reports.

California\'s Struggle With Insurance Exchanges Offers Lesson For National Reform

California"s experience with insurance exchanges could prove a valuable lesson for the nation"s flirtation with such pools for covering large numbers of people, The Wall Street Journal reports.

Also In Global Health News: Tanzania Drug Audit; WFP Might Suspend Flights; Acute HIV; HIV/AIDS In China

Global Fund Audit Reveals Expired, Missing Drugs In Tanzania

Detection Of "Prolonged Grief Disorder" May Help Bereaved Individuals

Identification of criteria for the detection of prolonged grief disorder

Bayer Schering Pharma Presents Positive Results Of Phase II Study With Riociguat

Positive data from a

Long-term Health And Social Outcomes For Neuroblastoma Survivors

Survivors of the childhood cancer neuroblastoma are eight times more likely to have chronic health conditions, less likely to be married, and more likely to have lower incomes than their siblings, according to a study published online July 31 in the Journal of the National Cancer Institute.

Parents Fear Errors During Children\'s Hospitalization

Nearly two-thirds of parents reported they felt the need to watch over their child"s care to ensure that medical errors are not made during their hospital stay, according to a study led by Beth A. Tarini, M.D., M.S., assistant professor of pediatrics at the University of Michigan Medical School.

Scientists Halt Epilepsy In Mice

Scientists at Leeds have prevented epilepsy caused by a gene defect from being passed on to mice offspring - an achievement which may herald new therapies for people suffering from the condition.

Regular Yoga Practice Is Associated With Mindful Eating

Regular yoga practice is associated with mindful eating, and people who eat mindfully are less likely to be obese, according to a study led by researchers at Fred Hutchinson Cancer Research Center.

For Struggling Single Moms, 3-Generation Households Are Better Than 2

Living in a three-generation household can significantly enhance the economic well-being of children, according to a new study from researchers at the University of Southern California and the University of Massachusetts, Boston.

Multimodality Treatments Effective In Halting Lung Cancer Progression

The world"s top lung cancer specialists, medical professionals and researchers are convening this week in San Francisco, CA for the 13th World Conference on Lung Cancer (WCLC), organized by the International Association for the Study of Lung Cancer (IASLC). As non-small cell lung cancer (NSCLC) is one of the most common types of lung cancer affecting a heterogeneous population, researchers have focused on multi-modality treatment regimens to improve patient outcomes. According to research showcased today at the WCLC, multi-modality, tailored treatment regimens increased patient survival rates compared to single-agent therapies.

Stanford Scientists Discover Bladder Cancer Stem Cell

Researchers at Stanford"s School of Medicine have identified the first human bladder cancer stem cell and revealed how it works to escape the body"s natural defenses.

\'SIRT\'ain Security: The Protein SIRT3 Protects The Heart

Sirtuin proteins have been shown to promote longevity in many organisms, and increased expression of one sirtuin protein, SIRT3, has been linked to increased human lifespan. New data, generated in mice, by Mahesh Gupta and colleagues, at the University of Chicago, Chicago, has revealed that Sirt3 helps protect the mouse heart.

Stem Cell \'Daughters\' Lead To Breast Cancer

Walter and Eliza Hall Institute scientists have found that a population of breast cells called luminal progenitor cells are likely to be responsible for breast cancers that develop in women carrying mutations in the gene BRCA1.

Holding Breath For Several Minutes Elevates Marker For Brain Damage

Divers who held their breath for several minutes had elevated levels of a protein that can signal brain damage, according to a new study from the Journal of Applied Physiology. However, the appearance of the protein, S100B, was transient and leaves open the question of whether lengthy apnea (breath-holding) can damage the brain over the long term.

As Swine Flu Deaths Rise Worldwide, US Schools Brace For "Nasty" Flu Season

Following a recent World Health Organization (WHO) report that over 1,000 of 1,154 people who have died worldwide from the 2009 H1N1 swine flu pandemic were in the Americas, schools in the US brace themselves for a "nasty" flu season.

What Is Cervical Cancer? What Causes Cervical Cancer?

Cervical cancer, or cancer of the cervix, is cancer of the entrance to the uterus (womb). The cervix is the narrow part of the lower uterus, often referred to as the neck of the womb. Cervical cancer occurs most commonly in women over the age of 30.

Web Site Helps Caregivers Navigate Medicare

The Department of Health and Human Services has created a web site called "Ask Medicare" to help caregivers navigate the often confusing Medicare system. CNN reports on the experience of Kim Mickens, a caregiver who used the site to help her mother, who has Alzheimer"s disease. "Medicare personnel helped her get some of the medical supplies she needed and also recommend a new Web site called Ask Medicare. Designed to give easy access to people taking care of elderly relatives, Ask Medicare provides information and links to services that are important to caregivers."

Louisiana Cuts Rates For Medicaid Providers

"Louisiana will start paying less money Tuesday to many private health care providers for taking care of Medicaid patients, a move the state health department estimates will save $86 million this year," The Associated Press/The Advocate reports. Adults in the program may also have to pay a small co-pay if they visit emergency rooms for non-emergency care. "The cuts come as the health department shrinks its spending to $7.9 billion in the new fiscal year that began July 1, down $240 million from last year. Nearly all the cuts will be levied on the Medicaid program for the poor, elderly and disabled. But Jerry Phillips, state Medicaid director, said the department believes it can cover nearly two-thirds of that gap through efficiencies and the continuation of other cuts made during the last budget year."

Commercialization Grant Awards Announced By Life Sciences Discovery Fund

The Life Sciences Discovery Fund (LSDF) has announced $300,000 in awards from its inaugural winter commercialization grant competition to support commercial translation of health-related technologies by two Washington state-based research teams. Commercialization grants are designed to facilitate the transition of promising ideas or technologies from Washington"s non-profit research sector into marketable products and services that can improve health, foster economic growth, and promote life sciences competitiveness in the state. The grants support proof-of-concept experiments and prototype development activities that are expected to lower the risk of commercialization and help new technologies cross the "valley of death" - that stage of the commercialization pathway where development funding is particularly scarce.

Filter-Feeding Bivalves Can Remove Avian Influenza Viruses From Water And Reduce Infectivity

Avian influenza (AI) viruses are believed to be transmitted within aquatic bird populations through contaminated water. This study determined that filter-feeding clams can remove AI virus from water and reduce infectivity.

Breast Cancer Risk May Be Affected By The Way You Eat

How you eat may be just as important as how much you eat, if mice studies are any clue.

Visual Processing \'Hinders Ability\' To Read Body Language: Autism Study

The way people with autism see and process the body language of others could be preventing them from gauging people"s feelings, according to new research.

Deet, The Popular Insect Repellent, Found To Be Neurotoxic

The active ingredient in many insect repellents, deet, has been found to be toxic to the central nervous system. Researchers writing in the open access journal BMC Biology say that more investigations are urgently needed to confirm or dismiss any potential neurotoxicity to humans, especially when deet-based repellents are used in combination with other neurotoxic insecticides.

Dr. David B. Samadi Introduces New Prostate Cancer Care Center For Robotic Surgery Patients At Mount Sinai Medical Center

The Mount Sinai Medical Center has a new re center for prostate cancer treatment. Led by David B. Samadi, M.D., Chief of the Division of Robotics and Minimally Invasive Surgery in the Department of Urology, the new state-of-the-art facility at 625 Madison Avenue in New York City specializes in pre- and post-surgery care for patients who undergo a robotic prostatectomy at Mount Sinai"s main campus. It also provides expertise in the treatment of other urologic cancers, including bladder and kidney. A multilingual staff offers assistance with patient travel arrangements, accommodations, and translation services when required.

The Advantages Of Nerve-Block Anesthesia Include Improved Pain Relief

When planning for surgery, patients too often don"t consider the kind of anesthesia they will receive. In fact, the choice of anesthesia can improve recovery, even outcomes.

Underweight And Very Severely Obese Patients At Risk Following Liver Transplantation

A recent study by doctors at the University of Washington explained that patients who are significantly underweight or very severely obese prior to liver transplantation are at increased risk of death following transplantation surgery. These findings, from the largest known observation of liver transplantation at the extremes of BMI, are published in the August issue of Liver Transplantation, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases.

Enormous Increase In NHS Spending On Management Consultants, UK

The amount of money PCTs (primary care trusts) are spending on management consultants has risen enormously, according to Pulse. In comparison to two years ago, the amount PCTs spend during the last financial year on external consultancy fees has risen threefold, according to figures compiled from 62 trusts.

Global Public Health Threat Continues From Lead-Based Consumer Paint

Although lead content in paint has been restricted in the United States since 1978, University of Cincinnati (UC) environmental health researchers say in major countries from three continents there is still widespread failure to acknowledge its danger and companies continue to sell consumer paints that contain dangerous levels of lead.

Personal Exposure Monitors Show Pharmacy Workers Inhale Drugs When Using Air Pressure-Activated Dispensing Machines

AlburtyLab released a report on its comprehensive evaluation of health risks for workers in pharmacies using air pressure-activated drug dispensing machines. The study tested pharmacy workers wearing personal exposure monitors (PEMs) while using the two leading types of air pressure-activated dispensing technologies - the McKesson/Parata Max and the McKesson/Parata RDS. This is the third major study conducted by AlburtyLab examining the issues relating to pharmacy worker exposure.

Methods For The Diagnosis Of Heart Failure Reviewed

A blood test (BNP) should be recommended over an electrocardiogram (ECG) for the diagnosis of heart failure suggests research published by the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme.

Not Only Does Our Gut Have Brain Cells It Can Also Grow New Ones, Study

A new US study has added to existing knowledge about the million or so brain cells in our gut by using lab mice to show that it can also grow

Novel H1N1 Influenza A (Swine Flu) Update For Arkansans

As of Wednesday, July 29, the Arkansas Department of Health (ADH) reported 150 lab-confirmed cases of novel H1N1 influenza A (Swine Flu) in Arkansas in residents from 38 of the state"s 75 counties. There have been no deaths due to H1N1 influenza A in Arkansas.

GeoVax Labs, Inc. Provides Clinical Studies Update

GeoVax Labs, Inc. (OTC Bulletin Board: GOVX), an Atlanta-based HIV/AIDS vaccine development company announced updates on its ongoing and planned human clinical trials.

Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results For Radezolid In Community-Acquired Pneumonia

Rib-X Pharmaceuticals, Inc. ("Rib-X" or the "Company"), a development-stage company focused on the discovery, development and commercialization of novel antibiotics for the treatment of antibiotic-resistant infections, today announced positive results from a Phase 2 clinical trial of radezolid in the treatment of community-acquired pneumonia (CAP).

Abnormal Brain Circuits May Prevent Movement Disorder

Most people who carry a genetic mutation for a movement disorder called dystonia will never develop symptoms, a phenomenon that has puzzled scientists since the first genetic mutation was identified in the 1990"s. Now, scientists at The Feinstein Institute for Medical Research have figured out why these mutation carriers are protected from symptoms of the disorder they have an additional lesion that evens the score.

Patient Recall Rates May Be Decreased By Digital Mammography Plus Digital Breast Tomosynthesis

Nationally, about ten percent of women in the US are recalled for a second mammogram after an abnormality is detected on the first one - for most women this can be very stressful. However the use of digital breast tomosynthesis and full-field digital mammography combined may be associated with a substantial decrease in recall rate, according to a study performed at UPMC in Pittsburgh, PA. Some researchers believe that digital breast tomosynthesis depicts the breast tissue in a way which may allow radiologists to identify some tumors which could be missed with standard two-dimensional mammography.

What Is Health? What Does Good Health Mean?

The English word "health" comes from the Old English word hale, meaning "wholeness, a being whole, sound or well,". Hale comes from the Proto-Indo-European root kailo, meaning "whole, uninjured, of good omen". Kailo comes from the Proto-Germanic root khalbas, meaning "something divided". Medilexicon"s medical dictionary has three definitions for health, the first being "The state of the organism when it functions optimally without evidence of disease or abnormality" (click here to read the other two).

Competitiveness And Perfectionism: Common Traits Of Both Athletic Performance And Disordered Eating

Timberline Knolls, one of the country"s leaders in the treatment of eating disorders, is recognizing well-known tennis star, Monica Seles, for disclosing her history with an eating disorder in her new book Get a Grip. Ms. Seles" display of courage and candor has the potential to help many others who have similar struggles, especially young female athletes.

Biotech Leaders, Patient Advocates Highlight Cutting-Edge HIV/AIDS Therapies, Need For Next Generation Treatments

Leaders in biotechnology research and patient advocacy joined forces today at the 2009 BIO International Convention to discuss the latest breakthroughs in HIV/AIDS treatments. Following a keynote speech by Sir Elton John focused on the needs of the HIV/AIDS community, representatives of biotech companies previewed the next generation of treatments while patient advocates reiterated the need for new therapies, particularly for those who have developed resistance to existing medications. Researchers are developing new therapies that are more effective in treating HIV/AIDS, including an AIDS vaccine and new methods of delivery that hold the potential to increase patient compliance.

What Is Endocarditis? Why Healthy Teeth Could Help Care For Your Heart

The word "endocarditis" comes from the word "endocardium". The endocardium is the innermost tunic of the heart, including the endothelium and subendothelial connective tissue; in the atrial wall, smooth muscle and numerous elastic fibers also occur.