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New Treatment Option At The Sarah Cannon Cancer Center Provides Hope For Inoperable Tumors
The Sarah Cannon Cancer Center (SCCC) at Centennial Medical Center last week began treating patients with a new non-invasive weapon in the battle against cancer. The Sarah Cannon Cancer Center is the first and only cancer center in Middle Tennessee to offer image-guided robotic stereotactic radiosurgery.

Actual Imaging Use Far Below President's Recommend 95 Percent Utilization Rate For Medicare
The amount of time imaging equipment is in use in outpatient settings does not approach use rates President Obama and the Medicare Payment Advisory Commission (MedPAC) recommend Medicare utilize to calculate reimbursement for imaging, according to data recently collected by the Radiology Business Management Association (RBMA), a national association of business professionals in radiology.
News of the day
Illinois Counties Facing Increases In STDs Among Teenagers; Bill Aims To Reduce Rates
Illinois health officials contend that images seen in the media, social influences, and a lack of "frank" discussion on STDs in schools, among other issues, might be contributing to increases in STD rates across the state, the State Journal-Register reports. "According to recently released data, new cases of chlamydia in Illinois reached an all-time high statewide in 2008 - 59,169 - while the number of gonorrhea cases outside Chicago has been rising in recent years and totaled 10,165 in 2008," the Journal-Register reports. In addition, about 35,000 state residents have HIV/AIDS, the article states. Charlie Rabins, chief of the STD program at the Illinois Department of Public Health, said a bill (SB 212) currently awaiting Gov. Pat Quinn"s (D) approval might help reduce STD rates. The bill "would allow what is called "expedited partner therapy," in which medical professionals who treat patients for gonorrhea or chlamydia can give those patients single-dose antibiotics to pass on to sexual partners without first examining the partners," according to the Journal-Register (Olsen, 7/27).

Diagnostics

Key Senate Panel Struggles To Reach Consensus

"The Senate Finance Committee, which is seeking a bipartisan compromise, has failed to reach an agreement" on health care reform, Bloomberg reports, "even as two House committees and a Senate panel cleared their versions of the legislation with only Democratic approval." The open-ended question of when, and what, the Finance panel will propose, has become the focus of Senators and the administration as the August recess nears with no deal in sight. Max Baucus, D-Mont., the Finance chairman, said a deal could come this week "at the earliest," a month after he originally planed to finalize a version of the bill, Bloomberg reports (Litvan and Jensen, 7/20).

Health Protection 2009 Conference - Programme Announced

The Health Protection Agency (HPA) has announced an innovative and wide-ranging programme for the Health Protection 2009 conference, which is taking place at Warwick University from 14th to 16th September.

Governors Question Medicaid Expansion While Some States Do More With CHIP

The New York Times reports that "The nation"s governors, Democrats as well as Republicans, voiced deep concern Sunday about the shape of the health care plan emerging from Congress, fearing that Washington was about to hand them expensive new Medicaid obligations without money to pay for them. The role of the states in a restructured health care system dominated the summer meeting of the National Governors Association here this weekend - with bipartisan animosity voiced against the plan during a closed-door luncheon on Saturday and in a private meeting on Sunday with the health and human services secretary, Kathleen Sebelius." After the meeting, Sebelius said "there"s a recognition that states don"t have cash right nowтЂ¦ i""s difficult to send states the bill if they don"t have the money."

Efforts To \'Fix\' Medicare Payments At Center Of Reform

The Wall Street Journal reports: "A plan to end a program that would cut government payments to doctors is emerging as the flash point in the debate over whether President Barack Obama"s effort to overhaul the health system would increase the federal budget deficit. The proposal was crucial to winning support from the politically powerful American Medical Association -- but it has also made it tougher to argue that the health overhaul would pay for itself. ... Health and Human Services Secretary Kathleen Sebelius, appearing on NBC"s "Meet the Press," said costs associated with the legislation could be reduced significantly if lawmakers included the administration"s recommendation to bolster the power of the Medicare Payment Advisory Commission, or MedPAC, to set Medicare payment policies.

Seegene\'s Seeplex(R) RV Multiplex PCR Tests Prove Effective For The Identification Of The New Influenza A H1N1

Building on its widely distributed multiplex PCR technology platform, Seegene is now providing healthcare systems worldwide with a powerful diagnostic test for effective identification of the new influenza A virus (swine H1N1).

Stem Cell Therapeutics Receives Clearance From Health Canada To Proceed With The Phase IIb Clinical Stroke Trial

Stem Cell Therapeutics Corp. (TSX VENTURE:SSS)("SCT" or "the Company") has received a No Objection Letter ("NOL") from Health Canada for the modified REGENESIS protocol using NTx-265 for a Phase IIb clinical trial treating acute ischemic stroke.

Obama Administration Silent On San Francisco Health Insurance Ordinance

"As the U.S. Supreme Court prepares to consider a restaurant group"s challenge to San Francisco"s health coverage ordinance, one voice is noticeably silent: the Obama administration"s," The San Francisco Chronicle reports. "In contrast to President George W. Bush"s Labor Department, which unsuccessfully urged a federal appeals court to overturn the groundbreaking law, the new administration submitted no arguments before the July 10 deadline for briefs supporting or opposing Supreme Court review. President Obama, meanwhile, has praised the San Francisco program, the first of its kind in the nation, while pressing Congress to enact comprehensive health coverage."

Local Meeting Held In California To Discuss HIV/AIDS Spending Priorities In Face Of Proposed State Budget Cuts

The Inland Empire HIV Planning Council, an agency that makes HIV/AIDS policy in Riverside and San Bernardino counties in California, has begun a three-day summit, where they will determine how funds - primarily from HHS - will be spent, the Riverside Press-Enterprise reports. The council, which oversees spending of more than $7 million for HIV/AIDS care and treatment in the counties, said proposed cuts to HIV/AIDS programs and Medi-Cal at the state level "could affect funding and treatment priorities set by the agency," the article states. Joe Acosta, co-chair of the council said they are looking for ways to make up for the expected shortfalls. The council distributes money to about a half dozen agencies in San Bernardino and Riverside counties that provide services to more than 6,800 HIV/AIDS patients, Acosta said" (Hines, 7/18).

Stop Seeing Red By Looking Through Blue-Tinted Lenses, UK

As the UK enters a summer of discontent, one company has a vision to make the outlook decidedly brighter - by looking at life through blue-tinted spectacles.

In Huntington\'s Patients, Transplanted Neurons Develop Disease-Like Pathology

The results of a recent study published in PNAS question the long-term effects of transplanted cells in the brains of patients suffering from Huntington"s disease. This study, conducted jointly by Dr. Francesca Cicchetti of Universitз© Laval in Quebec, Canada, Dr. Thomas B. Freeman of the University of South Florida, USA, and colleagues provides the first demonstration that transplanted cells fail to offer a long-term replacement for degenerating neurons in patients with Huntington"s disease.

First Minister Announces Funding For Second Phase Of Life Sciences Institute, Wales

First Minister Rhodri Morgan announced (date) that almost чЈ30 million of funding has been secured for phase two of the Institute of Life Science at Swansea University, with the promise of up to 650 jobs.

New Global Subsidy For Malaria Medicines Must Ensure Quality Of Care

A new subsidy designed to increase access to life-saving antiretrovirals

First Genetic Evidence For Why Placebos Work Presented By UCLA Scientists

Placebos are a sham - usually mere sugar pills designed to represent "no treatment" in a clinical treatment study. The effectiveness of the actual medication is compared with the placebo to determine if the medication works.

Can Pen And Paper Help Make Electronic Medical Records Better?

The results of a new study of the pen and paper workarounds employed by healthcare providers who use an electronic medical record system may help make electronic medical records even more useful to health-care providers and the patients they serve.

A Mother\'s Exposure To Urban Air Pollutants Can Affect Her Baby\'s IQ

Prenatal exposure to environmental pollutants known as polycyclic aromatic hydrocarbons (PAHs) can adversely affect a child"s intelligence quotient or IQ, according to new research by the the Columbia Center for Children"s Environmental Health (CCCEH) at the Mailman School of Public Health. PAHs are chemicals released into the air from the burning of coal, diesel, oil and gas, or other organic substances such as tobacco. In urban areas motor vehicles are a major of PAHs. The study findings are published in the August 2009 issue of Pediatrics.

Southampton Surgeons Honoured For Developing Keyhole Lung Cancer Surgery In The UK

Two Southampton surgeons who contributed to the development of keyhole surgery to treat early stage lung cancer have been internationally commended for their work.

National Health And Medical Research Council Funding For UQ Brain Injury Research, Australia

University of Queensland researchers will use a $2.5 million grant to help people who have suffered an acquired brain injury communicate with the world.

PBS Listing Of Antifungal Suspension Welcomed By Paediatricians

General Practitioners and specialists will be able to prescribe VFEND (voriconazole) oral suspension for immuno-suppressed adolescents and children following its listing on the Pharmaceutical Benefits Scheme (PBS) from 1 August 2009.

Affymax Announces Data Monitoring Committee Review Of Phase 3 Hematide Program

Affymax, Inc. (Nasdaq:AFFY) announced that the independent Data Monitoring Committee (DMC), which provides oversight for the Phase 3 program for Hematide, has completed another review and has informed the company that the cumulative safety data generated thus far from the EMERALD and PEARL Phase 3 trials support continuation of the studies. In the Phase 3 program, Hematide is being evaluated to treat anemia in chronic renal failure patients on dialysis and not on dialysis.

Pre-chewed Food Could Transmit HIV

Researchers have uncovered the first cases in which HIV almost certainly was transmitted from mothers or other caregivers to children through pre-chewed food. The of HIV in the pre-chewed food was most likely the infected blood in the saliva of the people who pre-chewed the food before giving it to the children. The researchers said their findings suggest that HIV-infected mothers or other caregivers should be warned against giving infants pre-chewed food and directed toward safer feeding options.

Budget Deal Slashes Health Care, Saddles California With Greater Costs Over The Long Term

The president of the California Medical Association, Dev A. GnanaDev, issued the following statement today in regards to the announced state budget deal:

Prehypertension, Obesity And Kidney Disease Risks

People with prehypertension are not at increased risk of kidney disease if their body mass index (BMI) is under 30.0 kg/m2, a first-ever examination of the combined effect of blood pressure and body weight on the risk of kidney disease shows.

ADHA Awards Presidential Citation To Minnesota State Senator, USA

The American Dental Hygienists" Association (ADHA) recently awarded Minnesota State Senator Ann Lynch with a presidential citation to recognize her extraordinary efforts in passing legislation which will establish new oral health providers in Minnesota.

Obama Administration\'s Filings On Asylum For Abused Foreign Women Brings \'Overdue Dose Of Clarity,\' Editorial Says

The Obama administration recently laid out "a clear but narrow pathway" toward asylum for foreign women who have experienced severe physical or sexual abuse, a New York Times editorial states, noting that the U.S. government has debated the issue for 15 years. According to the editorial, the "question is not the fact of persecution, but whether the women would qualify for protection under the law, which limits asylum to those who suffer due to their race, religion, nationality, political opinion or "membership in a particular social group."" It adds that attorneys general under former Presidents Clinton and George W. Bush "have gone both ways and in circles" in their decisions.Although "[n]ot all victims will qualify," the Obama administration "made it clear that some could," the editorial states. "A petitioner would have to demonstrate to a judge that domestic violence was widely tolerated by society and government in her country, that women were viewed as subordinate to men and that she had no place within its borders to find a safe haven," the editorial adds.Department of Homeland Security lawyers say the new definition could apply to a severely abused Mexican woman, identified only by her initials, whose asylum petition is before a San Francisco immigration court. The editorial notes that DHS "did not immediately recommend asylum" for the woman, but "it did urge that she be allowed to continue to gather evidence and to refine her case according to the standards it proposed." The editorial concludes, "Advocates who have fought for years to advance women"s rights are celebrating the department"s action, which brings reasoned compassion, and an overdue dose of clarity, to an issue of anguish and difficulty" (New York Times, 7/19).

House Democrats May Rethink Tax Increases

Democratic leaders may scale back a plan to tax the highest American earners, The New York Times reports.

Former Health Insurance Spokesman Criticizes Industry Practices

A former health insurance spokesman speaks out against insurance practices. The Wall Street Journal/Dow Jones reports: "Wendell Potter, former chief spokesman for health insurer Cigna Corp., describes himself in his Twitter bio as a "journalist who spent 20 years undercover as HMO PR flack, now writing all about it." While Potter chuckles about the line, he is serious about his foray into the U.S. health reform debate, where he is campaigning for a public health-plan option and, with mild delivery and tough words, targeting what he calls "deceptive and dishonest" tactics of a for-profit health insurance industry that"s fighting such a plan."

Hampton Court Allergy Screening A Success, UK

The National Pharmacy Association and Allergy UK provided free allergy screening to the public at Hampton Court Palace Flower Show from 7-12 July. Over 7,000 members of the public picked up information on community pharmacy allergy screening or asked for advice and 75 allergy screenings were carried out.

Today\'s Opinions And Editorials

A Better Remedy For Health Reform The Dallas Morning News

Antiretrovirals Can Be Used To Prevent Spread Of HIV/AIDS, Model Shows

In addition to acting as life-saving therapy to people living with HIV/AIDS, WHO researchers say antiretrovirals (ARVs) may also be able to prevent the spread of HIV, Health-e/allAfrica.com reports. Reuben Granich, of the WHO, used a model to estimate the use of ARVs for the prevention of HIV transmission, and presented his findings to delegates gathered at the 5th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention meeting in Cape Town, South Africa (Thom, 7/20).

Experimental Malaria Vaccine Using Weakened Malaria Parasite To Begin Human Trials

An experimental malaria vaccine created by "an approach pioneered more than 30 years ago but abandoned as wildly impractical" is about to be tested on humans, the Seattle Times reports. The vaccine, made up of weakened malaria parasites, provided 100 percent protection in mice. The Seattle Biomedical Research Institute"s (SBRI) Stefan Kappe - who is leading a group of researchers from Australia, Canada and Japan - said the group is "shooting for 90 percent-plus protection."

2009/044 NICE Guidance Recommends Tenofovir Disoproxil For Hepatitis B

The National Institute for Health and Clinical Excellence (NICE) has today (22 July) published final guidance recommending the use of tenofovir disoproxil for the treatment of people with chronic HBeAg-positive or HBeAg-negative hepatitis B in whom antiviral treatment is indicated.

2009/044 NICE Issues Final Guidance On The Use Of Rituximab For First Line Chronic Lymphocytic Leukaemia

The National Institute for Health and Clinical Excellence (NICE) has today (22 July) published guidance on the use of rituximab for the first line treatment of chronic lymphocytic leukaemia. The guidance recommends that rituximab should be considered asa possible first treatment for people with chronic lymphocytic leukaemia who are able to take fludarabine in combination with cyclophosphamide.

DART Trial Finds HIV Therapy Could Be Given Safely Without Routine Laboratory Tests To Save More Lives In Africa

The largest clinical trial of anti-retroviral therapy (ART) for people with HIV infection ever run in Africa has found that regular laboratory tests offer little additional clinical benefit to populations when compared to careful clinical monitoring.

Mabthera(R) (Rituximab) Available On NHS For UK\'s Most Common Leukaemia

The National Institute for Health and Clinical Excellence (NICE) today issued its recommendation for the use of MabThera (rituximab) in the UK"s most common form of leukaemia, chronic lymphocytic leukaemia (CLL).1,2,3 NICE"s final guidance recommends rituximab in combination with fludarabine and cyclophosphamide (FC) chemotherapy as an option for previously untreated patients with CLL.4 The addition of rituximab to FC chemotherapy has been proven to halt progression of the disease by 10.5 months longer than chemotherapy alone, and more than doubles the number of CLL patients achieving complete remission, compared to chemotherapy.5,6 More than 20,000 people in the UK are living with CLL and there are an estimated 3,700 new cases every year.7,8 Professor John Gribben, Consultant Haematologist and Medical Oncologist, Barts and The London NHS Trust, commented:

Weight Guidelines For Women Pregnant With Twins

Healthy, normal-weight women pregnant with twins should gain between 37 and 54 pounds, according to research from a Michigan State University professor who helped shape the recently released national guidelines on gestational weight gain.

NICE To Meet Again To Discuss Final Appraisal Determination Of Nexavar(R) (Sorafenib) For Patients With Hepatocellular Carcinoma (HCC), UK

The anticipated National Institute for Health and Clinical Excellence (NICE) decision on the Final Appraisal Determination (FAD) for Nexavar (sorafenib) for the treatment of advanced hepatocellular carcinoma (HCC) has been delayed, to allow consideration of the patient access scheme, Bayer Schering Pharma has agreed with the Department of Health.

Candela Receives Registration Approval To Market The Alex TriVantage Laser In Brazil

Candela Corporation (NASDAQ:CLZR) announced that it has received registration approval from the Brazilian National Health Surveillance Agency (ANVISA) to market the Candela Alex TriVantage multi-wavelength, q-switched laser system in Brazil.

FDA Designates Fast Track Status For Apaziquone (EOquin(R)) For Bladder Cancer

Spectrum Pharmaceuticals (NasdaqGM: SPPI) and Allergan, Inc. (NYSE:AGN) today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track Designation for the investigation of apaziquone (EOquin) for the treatment of non-muscle invasive bladder cancer, a form of bladder cancer localized in the surface layers of the bladder that has not spread to the deeper muscle layer. Approximately 70% of all newly diagnosed patients with bladder cancer have non-muscle invasive bladder cancer.1 More than one million patients in the United States and Europe are estimated to be affected by the disease.2

Milburn Report Ignores Crippling Cost Of Medical Education, Says British Medical Association

A new report aimed at increasing the number of doctors from lower income groups was branded a missed opportunity by doctor and medical student leaders after it failed to address the full of extent of the soaring financial cost of studying medicine in the UK.

Biomarkers May Help Predict Risk Of Alzheimer Disease In Patients With Mild Cognitive Impairment

Several cerebrospinal fluid (CSF) biomarkers showed good accuracy in identifying patients with mild cognitive impairment who progressed to Alzheimer disease, according to a study in the July 22/29 issue of JAMA.

Stem Cell Research Progress - cells that become part of the pancreas or part of the bile duct

Researchers from Cincinnati Children"s Hospital Medical Center have discovered that a specific gene - Sox17 - plays an important role in directing cells to become part of the pancreas or part of the bile duct (used in the digestion of food).

Physical Activity In Children Improves Their Sleeping Patterns

A research published ahead of print in the Archives of Disease in Childhood reports that every hour of the day children are inactive adds three minutes to the time it takes them to fall asleep.

Patient Has Speedy Recovery From New Heart Valve Procedure

For years, George Forschler knew the mitral valve in his heart was failing and would eventually need repair or replacement. Concerned about the risks associated with open heart surgery the traditional way to access a mitral valve he did his best to postpone the inevitable. Forschler, a retired U.S. Air Force Brigadier General who now heads a consulting firm, kept his heart healthy by exercising at the gym and doing weekend chores on his farm near here.

What Is Radiotherapy? What Is Radiation Therapy?

Radiotherapy is also known as radiation therapy, radiation oncology and XRT. It is used for treating cancer, thyroid disorders and some blood disorders. Approximately 40% of cancer patients undergo some kind of radiotherapy. It involves the use of beams of high-energy X-rays or particles (radiation) to destroy cancer cells. Radiotherapy works by damaging the DNA inside the tumor cells, destroying their ability to reproduce.

Advice For People With Asthma On Swine Flu Protection

Asthma UK"s team of clinical experts is offering important advice on how people with asthma can help protect themselves against swine flu now and into the autumn.

Blue Dogs: We Have Agreement With House Dems On Health Bill

Work on the House health care reform bill is slowing as Rep. Henry Waxman of California and fiscally conservative Blue Dog Democrats have come to an agreement on Medicare payments, The New York Times reports.

Costly Drugs Known As Biologics Prompt Exclusivity Debate

"A bitter Congressional fight over the cost of superexpensive biotechnology drugs has come down to a single, hotly debated number: How many years should makers of those drugs be exempt from generic competition?" The New York Times reports. "At issue are such drugs as Biogen Idec"s Avonex, for multiple sclerosis, which can cost more than $20,000 a year; Genentech"s Avastin for cancer, which can cost more than $50,000; and several Genzyme drugs for rare diseases that can cost $200,000 a year or more. тЂ¦ Because they are hard to copy exactly, they have not been subject to the generic competition that eventually knocks down the price of drugs like Lipitor and Prozac."

U.N. Reports $4.8B \'Record\' Aid Funding Shortfall

The U.N. on Tuesday said "it is running a record funding-shortfall of $4.8 billion for its aid operations in 16 crisis-ridden countries" and has received "less than half of the $9.5 billion it needs to carry out it humanitarian operations this year," VOA News reports (Schlein, 7/21).

Teens Are Exposed To Tobacco Content On Social Networking Sites

When teens surf the Internet, are they exposed to tobacco content or imagery? The study, "Exposure to Tobacco on the Internet: Content Analysis of Adolescents" Internet Use," tracked the Web pages viewed by 346 teens between the ages of 14 and 17 years. During a one-month period of data collection, these adolescents viewed 1.2 million Web pages. Of those pages, 0.72 percent contained tobacco or smoking content. Pro-tobacco content was found on 1,916 pages, anti-tobacco content on 1,572 pages, and complex and/or unclear content on 5,055 pages. Most of the tobacco-related content seen by teens was found on social networking sites. MySpace in particular represented 53 percent of the pages on which tobacco content was found. Previous studies have found a link between exposure to tobacco content in traditional media and adolescent smoking. The authors caution that as more communication occurs online in social networking sites, this may also impact adolescent smoking.

Abbott Launches New Instrument To Complete Family Of ARCHITECT Immunochemistry Analyzers

Today at the American Association for Clinical Chemistry"s Clinical Lab Expo in Chicago, Abbott (NYSE: ABT) announced the launch of a new diagnostic instrument - the ARCHITECT c4000 clinical chemistry analyzer which performs diagnostic tests that monitor general health including a patient"s levels of sodium, potassium, chloride and organ function.

Syphilis Making Comeback, Gonorrhea More Treatment Resistant, LSUHSC\'s Martin Says

Dr. David H. Martin, Professor and Chief of the Section of Infectious Diseases at LSU Health Sciences Center New Orleans School of Medicine, updated reporters and the National Foundation for Infectious Diseases on sexually transmitted diseases in the United States on July 22, 2009 at the National Press Club in Washington , DC. Dr. Martin, whose presentation was called, Sexually Transmitted Diseases: Neither Gone nor Forgotten, revealed significant information about STDs including Chlamydia trachomatis, gonorrhea, syphilis, and a relatively new STD, Mycoplasma genitalium.

Vyvanse CII Significantly Improved ADHD Symptoms For Children 13 Hours After Administration

Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, has announced that a study published online in the peer-reviewed journal Child and Adolescent Psychiatry and Mental Health found once-daily Vyvanse (lisdexamfetamine dimesylate) CII significantly reduced the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 to 12 from the first time point measured (1.5 hours) up to the last time point assessed (13 hours) after administration. In this pediatric analog classroom study, treatment with Vyvanse was associated with significant improvement in behavior and attention in children at each time point measured, with improvement at 13 hours after administration.

Oregon Researcher Puts New Focus On How Particles Of Colloidal Materials And Artificial Cells Interact

Applying biological molecules from cell membranes to the surfaces of artificial materials is opening peepholes on the very basics of cell-to-cell interaction.

Enhanced Digital Breast Imaging From US Navy-Funded Technology

A breakthrough technology adapted for breast cancer detection based in part on research originally sponsored by the Office of Naval Research (ONR) is set to air July 23 during a CNN International news segment on Vital Signs, a program hosted by Dr. Sanjay Gupta.

The Journal "Foot & Ankle Specialist" Accepted In Medline

Foot & Ankle Specialist (FAS), published by SAGE, has been accepted for inclusion in MEDLINE, the premier bibliographic database of the U.S. National Library of Medicine (NLM), containing more than 16 million journal article citations.

Macular Degeneration: The \'See Food\' Diet

Current research suggests that a diet high in omega-3 fatty acids may help prevent one of the leading causes of legal blindness among the elderly. The related report by Tuo et al, "A high omega-3 fatty acid diet reduces retinal lesions in a murine model of macular degeneration," appears in the August 2009 issue of the American Journal of Pathology.

First Cancer Congress Update A Huge Success

The 2009 Cancer Congress Update held at the Park Plaza hotel in central London was hailed a resounding success by clinicians from the worlds of breast, colorectal, lung, prostate and haematological cancer.

NICE Recommends VIREAD (tenofovir Disoproxil Fumarate) For The Treatment Of Chronic Hepatitis B, UK

The National Institute for Health and Clinical Excellence

Alzheimer\'s-Causing Amyloid And Bacteria Trigger Same Immune Response In The Brain

In a new study published today in the July issue of the journal Cell Host & Microbe, UC Davis researchers report that both amyloid plaques found in the brains of Alzheimer"s patients and structures made by some gut bacteria likely elicit the same response by human immune cells.

Gendux Molecular Limited Withdraws Its Marketing Authorisation Application For Contusugene Ladenovec Gendux (contusugene Ladenovec)

The European Medicines Agency has been formally notified by Gendux

Brits Abroad Leave Depressed Friends At Home

New research reveals Brits prefer to rearrange or cancel their summer holiday than go with a friend who has mental illness. The British would prefer to go on their summer holiday with a friend who has a criminal record than go with a friend who has a mental health problem, a new survey as part of the Time to Change campaign [1] has found.

Nexavar Approved In Japan For The Treatment Of Advanced Liver Cancer

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) announced that the Ministry of Health, Labour and Welfare (MHLW) in Japan has approved Nexavar(R) (sorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC), a type of liver cancer that accounts for 95 percent of all liver cancer cases in Japan(1). Nexavar is also currently available in Japan as an approved treatment for unresectable or metastatic renal cell carcinoma (RCC).

Study Reveals A Reprogrammed Role For The Androgen Receptor In Adndrogen-independent Prostate Cancer

The androgen receptor a protein ignition switch for prostate cancer cell growth and division is a master of adaptability. When drug therapy deprives the receptor of androgen hormones, thereby halting cell proliferation, the receptor manages to find an alternate growth route. A new study by Dana-Farber Cancer Institute and Ohio State University scientists demonstrates how.

NCDP Health Care Reform Recommendations Advocate For Diabetes Prevention, Treatment And Care

The National Changing Diabetes((R)) Program (NCDP), a program of Novo Nordisk, and several member associations today urged President Obama and members of Congress to make the prevention, detection and treatment of diabetes, one of the nation"s most pervasive and costly diseases, a priority in reforming the U.S. healthcare system.

Clinical Trial Tests Protein To Reduce Angina Pain

As part of a multi-center clinical trial, UC San Diego Medical Center is evaluating the safety and effectiveness of a potential new way to treat angina by injecting a protein that stimulates the growth of new oxygen-rich blood vessels directly into the heart. Angina is a debilitating form of chest pain caused by coronary artery disease that affects more than nine million Americans.

RCP President Reponds To New ONS Figures Suggesting That School Pupils Are More Likely To Drink Alcohol If They Live With Other Drinkers, UK

Responding to data in Smoking, drinking and drug use among young people in England, 2008 that suggests the likelihood of a pupil drinking alcohol increases with the number of drinkers per household, Professor Ian Gilmore, President of the Royal College of Physicians said:

Protein From Algae Shows Promise For Stopping SARS

A protein from algae may have what it takes to stop Severe Acute Respiratory Syndrome (SARS) infections, according to new research. A recent study has found that mice treated with the protein, Griffithsin (GRFT), had a 100 percent survival rate after exposure to the SARS coronavirus (SARS-CoV), as compared to a 30 percent survival for untreated mice.

Uphill Battle For Obama Sparks Comparisons To Clinton\'s Failed Reform Bid

"Will failing to reform health care have the same consequences for Obama"s administration as it did for Clinton"s?" CNN asks.

Analyses: CBO Director Elmendorf Becomes Center Of Attention

Several analyses today on the Congressional Budget Office, and its director, Douglas Elmendorf, who has been at the center of increasing debate over health care reform after the recent release of the CBO"s "score" of health system overhaul legislation. President Barack Obama met with him Monday in a move that has spurred Republican criticism.

Also In Global Health News: HIV Prevention In African Women; SIV In Chimps; Aid, Climate Partnerships; Obstetric Fistula

Reuters Examines Upcoming HIV Prevention Trial In Africa

Study Examines Efficacy Of Merck Drug On HIV Reservoirs

Patients who added Merck"s HIV drug Isentress to their regular daily HIV drug regimen "fared no better than those who added a placebo to the mix," as the drug failed to "reduce low-level reservoirs of HIV," in the body, according to findings presented at the International AIDS Society conference in Cape Town, South Africa, Bloomberg reports. As part of the 53-participant study led by Harvard University, researchers looked at patients whose viral loads were at undetectable levels and "were given either Isentress or a placebo for 12 weeks, then switched to the alternate agent for an additional 12 weeks. The study found no difference in low levels of the virus between the two groups, using a highly sensitive test," the article states. "The results are a setback for doctors looking for ways to seek and destroy the last vestiges of HIV, which aren"t reached by currently available drugs. Eliminating these so-called viral reservoirs may potentially cure patients, allowing them to stop taking daily medicines," according to Bloomberg (Pettypiece, 7/22).

Fresh Meats Often Contain Additives Harmful To Kidney Disease Patients

Uncooked meat products enhanced with food additives may contain high levels of phosphorus and potassium that are not discernable from inspection of food labels, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). This can make it difficult for people to limit dietary phosphorus and potassium that at high levels are harmful to kidney disease patients.

Identifying Pathways In The Brain To Understand The Underlying Molecular Mechanism Of Huntington\'s Disease

Florida Atlantic University researcher Dr. Jianning Wei, assistant professor of biomedical sciences in the Charles E. Schmidt College of Biomedical Science at FAU, has received a grant from the National Institutes of Health (NIH) to further her research into the molecular mechanisms of Huntington"s disease (HD). Named after American physician George Huntington, HD is a highly complex genetic, neurological disorder that causes certain nerve cells in the brain to waste away. The disease, characterized by a selective loss of neurons in the brain, affects the basal ganglia, which controls motor control, cognition, learning and emotions. It also affects the outer surface of the brain, or the cortex which controls thought, perception, and memory. Wei and her colleagues are working to identify the pathways in the brain that are altered in response to mutant proteins, as well as to understand the cellular processes impacted by the disease in order to facilitate the development of effective pharmacological interventions.

Camera Phones Can Help Doctors Diagnose Uncommon Problems

Taking photographs or video of unusual symptoms on an ordinary camera phone can help doctors diagnose uncommon problems, say researchers in an article published on bmj.com.

Queensland Researchers And Practitioners To Discuss Public Health, Australia

How much disease costs Australia will be the focus of a keynote address by UQ"s Professor Theo Vos at today"s Public Health Association of Australia Queensland State Conference.

The National Committee To Preserve Social Security And Medicare - Protecting The Health And Economic Future Of Older Americans

"As the President himself has said, America does not face an entitlement

Anthrax Attack Requires Early Detection & Quick Response

A large attack on a major metropolitan area with airborne anthrax could affect more than a million people, necessitating their treatment with powerful antibiotics. A new study finds that in order for a response to be effective, quick detection and treatment are essential, and any delay beyond three days would overwhelm hospitals with critically ill people.

Merck KGaA Submits Application For Cladribine Tablets As Multiple Sclerosis Therapy In Europe

Merck KGaA announced the submission of a marketing authorization application (MAA) to the European Medicines Agency (EMEA) for Cladribine Tablets, Merck"s proprietary investigational oral formulation of cladribine, as a therapy for patients with relapsing-remitting multiple sclerosis (MS). Cladribine Tablets could become the first orally administered disease-modifying therapy available for patients with MS, as all disease-modifying therapies currently approved for the treatment of MS are injectable.

BSI-201 Enters Phase III In Metastatic Triple Negative Breast Cancer

Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) and its wholly owned subsidiary, BiPar Sciences, announced the initiation of the pivotal Phase III trial for BSI-201 in combination with chemotherapy in patients with metastatic triple-negative breast cancer (mTNBC), defined by tumors lacking expression of estrogen, progesterone receptors and without over-expression of HER2. BSI-201 is a novel investigational targeted therapy which inhibits poly (ADP-ribose) polymerase (PARP1), an enzyme involved in DNA damage repair.

What Is Anemia? What Causes Anemia?

When the number of red blood cells or concentrations of hemoglobin are low a person is said to have anemia. Hemoglobin is a protein (metalloprotein) inside the red blood cells that contains iron and transports oxygen.

High-Grade Prostate Cancer Outcomes Treated With Combination Of Brachytherapy, External Beam Radiotherapy And Hormonal Therapy

UroToday.com - In the online edition of the BJU International, Dr. Richard Stock and colleagues from Mt. Sinai School of Medicine in New York reported on their outcomes using combined radiotherapy approach to men with high-risk prostate cancer (CaP).

USA Today Examines \'Incendiary Debate\' Over Abortion Rights

Nearly 40 years after the Supreme Court"s decision in Roe v. Wade, the "incendiary debate over abortion rights endures" and continues to manifest itself in a number of ways, USA Today reports. According to a recent USA Today/Gallup Poll, 78% of U.S. residents want abortion to be legal under at least some circumstances, with 21% saying it should be legal under any circumstance. According to the poll, 18% of respondents said that they want abortion always to be illegal. The poll also found that 46% of U.S. residents self-identify as "pro-choice," while 47% self-identify as "pro-life."Nancy Northup, president of the Center for Reproductive Rights, said, "The enduring divide represents the reality that there are fundamental religious differences on the issue of abortion that do not exist on, say, campaign finance or even on health care." Americans United for Life President Charmaine Yoest said that abortion-rights opponents are mobilizing to urge congressional lawmakers to exclude abortion coverage and funding from any federal health reform legislation.During the confirmation hearings of Supreme Court nominee Sonia Sotomayor, the judge said that she does not believe previous court rulings on abortion rights have ended the national controversy surrounding the issue. According to USA Today, Sotomayor, who has never ruled on the issue, declined to reveal her personal position on abortion rights. Several antiabortion-rights advocates also protested during Sotomayor"s hearings (Biskupic, USA Today, 7/24).In addition, the Center for Reproductive Rights this week released a report that found physicians and employees of health care clinics providing abortion services in six states -- Alabama, Mississippi, Missouri, North Dakota, Pennsylvania and Texas -- face an increasing level of harassment and death threats. The report was based on a four-month investigation (AP/Houston Chronicle, 7/23). The report was tied to the murder of Kansas abortion provider George Tiller (USA Today, 7/24). Operation Save America Director the Rev. Flip Benham, whose group is mentioned in the report, said the center is trying to limit the free-speech rights of abortion-rights opponents (AP/Houston Chronicle, 7/23).

Enthusiasm For Medical Homes Gradually Picks Up

Insurers are testing a concept called "medical home" that uses electronic records and coordinates care, and could transform the delivery of health care. Advocates say such medical homes could save consumers time and money and insurers back the idea. Meanwhile, skeptics say financial savings still need to be proven and incentives need to put into the system to encourage such care.

\'Tasting\' Mechanism Used By Airway Cells To Detect And Clear Harmful Substances

The same mechanism that helps you detect bad-tasting and potentially poisonous foods may also play a role in protecting your airway from harmful substances, according to a study by scientists at the University of Iowa Roy J. and Lucille A. Carver College of Medicine. The findings could help explain why injured lungs are susceptible to further damage.

Some Strategic Limitation On Individual Knowledge Could Improve The Performance Of A Large And Complex Group, Ant Study Suggests

In a study released online on July 22 in the journal Proceedings of the Royal Society: Biological Sciences, researchers at Arizona State University and Princeton University show that ants can accomplish a task more rationally than our - multimodal, egg-headed, tool-using, bipedal, opposing-thumbed - selves.

Management Of Pandemic H1N1 In Swine Herds

The Canadian Food Inspection Agency (CFIA), in collaboration with stakeholders, trading partners, and the public and animal health communities, has refined its approach to managing cases of the pandemic H1N1 2009 virus in swine.

Surgery, Oral Devices Associated With Improvement In Sleep Breathing Disorder

Treatment with surgery or an oral appliance that adjusts the jaw is associated with improvements in obstructive sleep apnea, a condition caused by blocked upper airways in which patients periodically stop breathing during sleep, according to two reports in the May issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

Transition To Electronic Health Records Is Now Complete At Randolph Medical Center - Alabama Department Of Public Health

A successfully completed electronic health record pilot project at Randolph Medical Center in

UK\'s Poorest Twice As Likely To Have Diabetes And Its Complications

The poorest people in the UK are 2.5 times more likely to have diabetes at any age than the average person, a new Diabetes UK report reveals today. And once they have the condition, those in the most deprived homes are twice as likely to develop complications of diabetes as those in the least deprived.

Evidence Linking Agent Orange, Parkinson\'s, Heart Disease "Limited Or Suggestive", Report

Writers of a new report found "limited or suggestive evidence" that exposure to Agent Orange and other chemicals used in the Vietnam War is

Nanobiotix Reports Exciting Preclinical Results Using Its NanoXray Therapeutics Technology To Destroy Tumors

Nanobiotix, an emerging nanomedicine company, announced exciting preclinical results using its patented nanoXray therapeutics platform to fight tumors. The preclinical study, performed at Institut Gustave Roussy, one of Europe"s leading cancer treatment centers, showed that an intratumoral injection of NBTXR3 nanoparticles and activated via standard radiation therapy led to complete tumor regression in mice at 60 days, compared to zero tumor regression in mice treated with xray only or NBTXR3 only. The study was led by principal investigator, Jean Bourhis, M.D., Ph.D. a prominent radiation oncologist and researcher at Institut Gustave Roussy.

University Of Queesnland\'s Speech Pathology Students Teach The Art Of Smooth Talking, Australia

A group of UQ speech pathology students recently ran an intensive treatment program for people who stutter.

American Medical Student Association Rejects New Organization Dedicated To Limiting Conflict Of Interest Regulation

The American Medical Student Association (AMSA) rejects the objectives of the Association of Clinical Researchers and Educators (ACRE), a newly formed organization that seeks to limit conflict of interest regulations. AMSA, the nation"s oldest and largest, independent association for physicians-in-training, is calling on the medical profession to continue to reduce the influence of pharmaceutical and medical device industry promotional activities, which research has proven to negatively affect patient care.

British Veterinary AssociationGuide To Partnerships In Veterinary Practice, UK

Continuing efforts to help its members form lasting and profitable partnerships and pre-empt disputes in veterinary practice, the British Veterinary Association (BVA) has revised its "Guide to partnerships in veterinary practice". It will be of particular interest to vets buying into a partnership for the first time and will also be helpful to partners revising their existing agreement.

Highmark Provides Pediatricians With Res To Combat Childhood Obesity

Childhood obesity causes lifelong illness, leads to serious health complications in young adults and can lead to premature death in adulthood due to medical conditions such as diabetes, heart disease and hypertension. In addition to its significant human toll, childhood obesity alone costs the nation"s health care system some $14 billion annually.

Obesity And Diabetes Reduced By Common Allergy Drug In Mouse Model

Crack open the latest medical textbook to the chapter on type 2, or adult-onset, diabetes, and you"ll be hard pressed to find the term "immunology" anywhere. This is because metabolic conditions and immunologic conditions are, with a few exceptions, distant cousins.

Oregon Hospital Building Boom Slows Down

"Oregon"s hospital spending boom is winding to a close," as hospitals cut back on projects, Portland Business Journal reports. "Portland-area hospitals have opened, started construction on, or announced expansions costing at least $1.3 billion in the past 18 months. Projects include cancer treatment centers, cardiac units and pediatric care facilities. Now, spurred by economic concerns, health organizations are cutting back. ... It doesn"t make financial sense to embark on major new projects until the economy improves and hospital administrators know how health care reforms may affect their operations, said Providence Chief Operating Officer Terry Smith."

Washington, D.C., Church Addresses HIV Stigma, Teaches Safe Sex To Black, Gay Congregation

The Washington Post on Sunday featured Washington D.C.,-based Inner Light Ministries, a 16-year-old black community church with about 100 members, where many go "to share their experience of being black and gay, living and loving in a city where HIV and AIDS lurk in epidemic proportions. тЂ¦" Some members of the congregation, as well as four of its leaders including Bishop Rainey Cheeks are HIV-positive. Cheeks teaches safe sex as a part of his sermons and the church provides condoms to its members. The article also discusses the stigma associated with HIV among gay black men. "Some men are reluctant to reveal their health status to possible partners for fear of being rejected," according to the Post. "That attitude, Cheeks said, is part of why gay black men in the District are disproportionately affected by HIV and AIDS. And why he has to keep preaching the message of safe sex," the article states (Fears, 7/26).

Oakland, Calif., Conference Targets Black Women For HIV/AIDS Awareness, Prevention

The Oakland, Calif., chapter of the National Coalition of 100 Black Women on Saturday held a daylong conference, "Sistahs Getting Real About HIV/AIDS," that addressed HIV/AIDS among black women, the San Francisco Chronicle reports. The conference "focused on two issues that might seem contradictory: first, to convince women that they must take special precautions to protect themselves, and second, to let them know that an HIV diagnosis is not a death sentence," according to the Chronicle. Keynote speaker of the conference Tony Wafford, director of health and wellness for the National Action Network, said black women need to be more vocal with their partners about practicing safe sex and getting tested for HIV. Organizers noted that black women also "must address the stigma associated with HIV before they can talk openly about the risk of infection with their partners," the article states (Allday, 7/25).

Poor Health Habits Discovered In Most Older Long-Term Cancer Survivors

A new study finds that most older long-term cancer survivors who are interested in diet and exercise actually have poor health habits. The study also reveals that those survivors who do exercise and watch their diet have improved physical health and quality of life. Published in the September 1, 2009 issue of Cancer, a peer-reviewed journal of the American Cancer Society, the research indicates that greater efforts are needed to encourage elderly cancer survivors to live healthier lives.

Antipsychotic Drugs Associated With High Blood Sugar In Older Adults With Diabetes

Older patients with diabetes who take antipsychotic medications appear to have an increased risk of hospitalization for hyperglycemia (elevated blood glucose level), especially soon after beginning treatment, according to a report in the July 27 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

The Cytoplasmic Talk Of Retroviruses Helps Them Spread From Cell To Cell

It is known that Retroviruses, such as HIV, that are already within cells

The Preclinical Natural History Of Serous Ovarian Cancer: Defining The Target For Early Detection

Ovarian cancer kills approximately 15,000 women in the United States every

U.S. Residents To Pay Greater Share Of Employer-Sponsored Health Insurance Coverage In 2009, Report Finds

U.S. residents enrolled in employer-sponsored health plans will contribute an average of 41% of their health care costs in 2009, the largest share to date, according to a study released on Monday by the Seattle-based actuarial consulting firm Milliman, the Minneapolis Star Tribune reports. The report looked at employer-sponsored preferred provider organizations plans in 14 metropolitan cities. Researchers found that total medical costs for a typical family of four in 2009 are expected to reach $16,771, up by 7.4% from 2008. Employers are expected to pay $9,947 of that, and employees are expected to contribute $4,004 through health plan premiums and another $2,820 through out-of-pocket costs such as copayments and deductibles. In addition, the report found that consumption of medical services is expected to be flat this year for the first time ever. Kate Fitch, a consultant at Milliman, attributed the slowdown to better disease management and wellness programs. However, per unit medical costs are up, and hospital outpatient care had the highest growth in 2009 (Yee, Minneapolis Star Tribune, 5/18).The report also found variations in medical costs by city. Miami had the highest health costs for a family of four at an average of $20,282 in 2008, almost 21% higher than the national average, followed by New York City at $19,684. Phoenix had the lowest at $14,857 (Dorschner, Miami Herald, 5/19).The report is available online.

Sufferers Of Lung Diseases May Be Helped By Placenta-Derived Stem Cells

An Italian research team, publishing in the current issue of Cell Transplantation (18:4), which is now available on-line without charge at http://www.ingentaconnect.com/content/cog/ct, has found that stem cells derived from human placenta may ultimately play a role in the treatment of lung diseases, such as pulmonary fibrosis and fibrotic diseases caused by tuberculosis, chemical exposure, radiation or pathogens. These diseases can ultimately lead to loss of normal lung tissue and organ failure. No known therapy effectively reverses or stops the fibrotic process.

University Of Queensland Researcher Trials New Treatments For Whiplash

For physiotherapist Associate Professor Michele Sterling, treating whiplash is all about thinking outside of the box.

Why Measuring Absolute Risk Of Fracture Could Save Many Broken Bones

A person"s absolute risk of fracture over the next 5 or 10 years can be predicted with reasonable accuracy according to their age, sex, bone density and history of fractures and falls.

Galaxy Zoo Hunters Help Astronomers Discover Rare \'Green Pea\' Galaxies

A team of astronomers has discovered a group of rare galaxies called the "Green Peas" with the help of citizen scientists working through an online project called Galaxy Zoo. The finding could lend unique insights into how galaxies form stars in the early universe.

Inovio Biomedical Universal Dengue DNA Vaccine Demonstrates Strong Immune Responses Against All Four Serotypes

Inovio Biomedical Corporation (NYSE Amex: INO), a leader in DNA vaccine design, development and delivery, announced that the company"s first SynCon dengue virus DNA vaccine induced neutralizing antibody responses against all four distinct serotypes of dengue viruses that are transmitted to humans by mosquitoes. Currently there is no commercially available vaccine or antiviral drug against dengue virus infections. The results were published in Vaccine, July 3, 2009, in a paper entitled, "Development of a novel DNA SynCon tetravalent dengue vaccine that elicits immune responses against four serotypes" (Ramanathan MP, Kuo YC, Selling BH, Li Q, Sardesai NY, Kim JJ, Weiner DB).

Celsion And Yakult Honsha Announce Start-up Of Japanese Clinical Trial Sites In Celsion\'s Global Phase III ThermoDox(R) Trial For Primary Liver Cancer

Celsion Corporation (NASDAQ: CLSN) and Yakult Honsha Co., Ltd. (Tokyo: 2267) announced that Celsion"s global Phase III ThermoDox trial for the treatment of primary liver cancer will be extended to Japan by Yakult"s expertise. This is an important step towards a potential application to market the drug in Japan. Yakult Honsha is the exclusive licensor of Celsion"s ThermoDox in Japan.

Ongoing Study Shows That Endovascular Therapy Is Associated With High Cure Rate For Childhood Eye Cancer

Expanded results of a study conducted on children with eye cancer (retinoblastoma) shows that chemotherapy delivered through endovascular (through the vessel) means not only successfully cures the cancer in a majority of cases, but achieves this cure with preserved vision. Study outcomes were presented this week at the Society of NeuroInterventional Surgery (SNIS) 6th Annual Meeting in Boca Raton, FL by lead author Pierre Gobin, Professor of Radiology in Neurosurgery and Neurology at the Weill Cornell Medical Center at New York Presbyterian Hospital in New York City.

Neurointerventionists Expand Research To Quality Of Life In Aneurysm Patients Following Minimally Invasive Coiling Treatment

Since the groundbreaking 2002 ISAT International Subarachnoid Aneurysm Trial (ISAT) which ultimately was halted due to overwhelming evidence that minimally invasive coiling (an endovascular therapy) was, on average, superior to traditional surgical clipping in the treatment of brain aneurysms many studies have continued to prove the short and long-term viability of this procedure. Further technical refinements for coiling are underway all over the world.

The Formula For Sustainable Healthcare Reform

A new report, released by the Manhattan Institute"s Center for Medical Progress and authored Douglas Holtz-Eakin, the former Director of the Congressional Budget Office, makes the fiscal and political case for bipartisan healthcare reform. Holtz-Eakin addresses dysfunctions in the existing healthcare delivery system; provides solutions to expanding access to affordable private health insurance in an incremental and fiscally responsible manner; and shows how improving market-based options will lead to better consumer access to information on healthcare quality. He argues that the only way to fix our broken healthcare system is through reforms that incentivize competition and pay for quality care.