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HHS Secretary Sebelius Picks Georgetown's Mann To Head Center For Medicaid And State Operations
HHS Secretary Kathleen Sebelius on Friday appointed Cindy Mann, director of Georgetown University"s Center for Children and Families, to head the Center for Medicaid and State Operations, a division of the Centers for Medicare and Medicaid Services, BNA reports. Mann is a former director of the Family and Children"s Health Programs at CMSO from 1999 to 2001. Sebelius said Mann has been "instrumental in recent efforts to expand health care coverage in our country." She added that Mann"s "knowledge of health care issues and management experience will be a great asset to CMSO and to the millions of Americans who rely on Medicaid" (BNA, 6/1).

Updated Position Paper On Vegetarian Diets Released By The American Dietetic Association
The American Dietetic Association has released an updated position paper on vegetarian diets that concludes such diets, if well-planned, are healthful and nutritious for adults, infants, children and adolescents and can help prevent and treat chronic diseases including heart disease, cancer, obesity and diabetes.
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NYT/CBS News Poll Examines Public Opinion On Sotomayor, Shows Support For Abortion Rights
Three weeks after President Obama named Judge Sonia Sotomayor as his nominee to the Supreme Court, 53% of U.S. adults say they do not know enough about her to determine whether they would support her confirmation, according to a New York Times/CBS News poll released Wednesday, the New York Times reports. The question was one of many in the national telephone poll of 895 adults, which explored a broad range of issues related to Obama"s first five months as president. According to the poll, 48% of participants said that Sotomayor"s opinions on issues like abortion and affirmative action are important information that should be known ahead of her confirmation hearing, which is scheduled to begin July 13. The poll found that 74% of participants believe it is very or somewhat important for the Supreme Court to reflect the nation"s diversity. The Times reports that although Sotomayor"s nomination and the recent murder of Kansas abortion provider George Tiller have "injected a fresh dynamic into the national abortion debate," the new poll shows that there has been little change in public opinion on abortion rights in the past 20 years. Thirty-six percent of participants said that abortion should be generally available, 41% said it should be available but with increased restrictions and 21% said it should be prohibited. Among Democratic voters, 71% said that Roe v. Wade should not be overturned, while Republican voters were "closely divided," the Times reports. The poll was conducted from June 12 to June 16 and has a margin of sampling error of plus or minus three percentage points (Zeleny/Sussman, New York Times, 6/18).


Also In Global Health: Text Messages For Health; Chagas Disease; Infant, Maternal Mortality In Botswana; Community Health Progs In Africa; Swaziland

UN Launches Pilot Study In Uganda That Uses Text Messages To Promote Public Health

CBO Director May Help Determine Fate Of Health Care

Several newspapers had articles on major players in health care reform. Douglas W. Elmendorf, director of the Congressional Budget Office, has "toiled for much of his career in the anonymous bowels of the nation"s economic superstructure," the Washington Post reports. But now, some lawmakers "think he holds the fate of public policy in his hands." After delivering a "skeptical analysis of a stimulus package intended to rescue the U.S. economy" and forecasting "bigger-than-expected losses from a $700 billion bailout of the U.S. financial system, Elmendorf now "faces the toughest task of his brief tenure: attaching a price to a monumental overhaul of the nation"s health-care system." Sen. Max Baucus, D-Mont., has "publicly lectured Elmendorf, saying he has a moral duty to be "creative" and deliver the favorable budget estimates "we have to have" to win broad support." But Elmendorf says "his office will offer an objective analysis, "without regard to the political consequences."" Elmendorf told the Post that his office would provide the information, but the decision is in the hands of Congress. "CBO is not going to make or break health-care reform," he says.

Putting A Price Tag On Reform Spreads Unease

Taxes, fees for business and spending cuts could help lawmakers pay the $1-trillion-plus cost of health reform, but those possibilities have spurred a behind-the-scenes lobbying fight on Capitol Hill, and caused a fair share of anxiety among many interest groups, the Los Angeles Times reports. For instance, Anchor Brewing Co., a San Francisco beer-maker, chocolate milk sellers and labor unions have all attacked lawmakers over new tax proposals for liquor, soft drinks and employer-sponsored benefits that would affect their industries.

Warmer Weather Brings Health Concerns, Iowa

With schools dismissing for summer and summer activities underway, the Iowa Dept. of Public Health (IDPH) reminds Iowans to be aware of illnesses and health concerns that are typically associated with warmer weather. Increased outdoor activities mean increased potential for exposure to ticks, waterborne illnesses like Cryptosporidiosis (Crypto) and other diseases. "Everyone is eager to get outdoors," said IDPH Medical Director, Dr. Patricia Quinlisk. "Being aware of spring and summer health concerns is important, especially when simple precautions can help prevent illnesses."

Cancer May Be Stopped In Its Tracks By MicroRNA Replacement Therapy

A new study suggests that delivering small RNAs, known as microRNAs, to cancer cells could help to stop the disease in its tracks. microRNAs control gene expression and are commonly lost in cancerous tumors. Researchers have shown that replacement of a single microRNA in mice with an extremely aggressive form of liver cancer can be enough to halt their disease, according to a report in the June 12 issue of the journal Cell, a Cell Press publication.

Why Smoking Increases The Risk Of Heart Disease And Strokes

Researchers at Charles Drew University of Medicine and Science in Los Angeles and Western University of Health Sciences in Pomona have discovered a reason why smoking increases the risk of heart disease and strokes.

The First French Software Program Enabling \'Action Through Thought\' - OpenViBE

Operating a computer by thought alone was unimaginable ten years ago, but this incredible feat is now possible. Financed by the ANR (the French national research agency) OpenViBE is the first French multi-partner project on brain-computer interfaces. With support from INRIA (the French national institute for research in computer science and control) and Inserm (the French national institute of health and medical research), OpenViBE has successfully perfected a free software programme with highly promising applications.

Link Between Symptoms Of Depression In Obese Children And Elevated Cortisol

A new study connects abnormalities of the "stress" hormone cortisol with symptoms of depression in obese children, and confirms that obesity and depression often occur together, even in children. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.

Fatness In Blacks Overestimated By Widely Used Body Fat Measurements

The body mass index (BMI) and waistline measurement overestimate obesity in blacks, according to a new study. The results, which were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C., suggest that conventional methods for estimating body fat may need to become race-specific.

Risk Of Discrimination For Individuals With Family History Of Genetic Disease

A research published on bmj.com reports that individuals with a family history of genetic disease are frequently discriminated by their relatives, friends and also by insurance companies.

New Health Secretary Sets Out Vision For A People Centred NHS, UK

A new era in the National Health Service that builds on targets achieved and prioritises quality of care was set out by new Health Secretary Andy Burnham today.

Infection Prevention Text Updated, Improved - The APIC Text Of Infection Control And Epidemiology

More than 300 infection prevention experts have completed a text that serves as one of the most valuable tools for infection preventionists throughout the world, the APIC Text of Infection Control and Epidemiology. The 1,700-page document, now in its 3rd edition, has been completely revised and is now available, offering a concise information re containing more than 120 expanded and enhanced chapters.

Metatastic Breast Cancer - New Dosing Schedule Suggests Potential Amplified Clinical Activity Of Novel KSP Inhibitor

Cytokinetics, Incorporated (NASDAQ: CYTK) announced that a

APHA Commends Senate Passage Of Tobacco Legislation, USA

Statement from Georges C. Benjamin, MD, FACP, FACEP (E), Executive Director, American Public Health Association, "The American Public Health Association applauds the Senate for today passing the Family Smoking Prevention and Tobacco Control Act. The legislation will protect the health of Americans, particularly children, by giving the Food and Drug Administration (FDA) the authority to regulate tobacco products.

Chance Of Fetal Complications Following Accidents Not Increased By Automobile Restraints

It is well established that seat belts save lives. However, many pregnant women do not wear seat belts, for fear that the belt itself could injure the baby in a car crash. But is this actually the case? Does the seat belt put the baby at risk?

Ambulance Diversion Studied

When a hospital"s emergency department is overcrowded with seriously sick and injured patients, it may "go on diversion," re-routing ambulances to other emergency departments. But the benefits of "diversion" are largely unproven. Often those emergency departments are just as crowded, and the greater distance to that other hospital can worsen the condition of some patients.

Rogers Media Partners With AstraZeneca Canada And Physical And Health Education Canada To Promote New Children\'s Wellness Program At My BestTM

Rogers Media is proud to join AstraZeneca Canada and Physical and Health Education Canada (PHE Canada) as a presenting partner of the school-based children"s wellness initiative, At My Best. The program addresses three key areas of wellness-physical, nutritional and emotional-and empowers teachers, parents and caregivers to inspire and motivate children and their families to make healthier choices today and develop lifelong healthy habits.

Frontal Cerebral Hypothermia Found To Be Possible New Treatment For Insomnia

Insomnia is associated with increased frontal cerebral metabolism during Rapid Eye Movement (REM) sleep. Cerebral hypothermia, or cooling of the brain, has been found to reduce cerebral metabolism in other medical conditions, but its effects in insomnia are unknown.

Women With Stable Marriages And New Partners Enjoy Better Sleep

Women who have stable marriages or who have recently gained a partner reported better sleep than women who are unmarried or who have lost a partner, according to a new University of Pittsburgh study.

Treatment Lightens Teenage Depression\'s Heavy Toll, Lowers Suicide Risk, Says Packard/Stanford Child Psychiatrist

Help is available - and essential - for teenagers struggling with depression and suicidal thoughts.

Ginseng -- Nature\'s Anti-Inflammatory?

Laboratory experiments have demonstrated the immunological effects of ginseng. Researchers writing in BioMed Central"s open access Journal of Translational Medicine have shown that the herb, much used in traditional Chinese and other Asian medicine, does have anti-inflammatory effects.

Ardea Biosciences Announces Positive Interim Phase 2a Results For Lead Gout Drug, RDEA594

Ardea Biosciences, Inc. (Nasdaq:RDEA) announced positive interim results from an ongoing Phase 2a, proof-of-concept study of RDEA594, its lead product candidate for the treatment of hyperuricemia and gout, as well as additional positive results from completed Phase 1 studies of RDEA594 in normal, healthy volunteers. The Phase 1 results, along with additional preclinical data, were presented at the Annual European Congress of Rheumatology hosted by the European League Against Rheumatism (EULAR) in Copenhagen, Denmark.

Individuals Who Apply Pesticides Are Found To Have Double The Risk Of Blood Disorder

A study involving 678 individuals who apply pesticides, culled from a U.S. Agricultural Health Study of over 50,000 farmers, recently found that exposure to certain pesticides doubles one"s risk of developing an abnormal blood condition called MGUS (monoclonal gammopathy of undetermined significance) compared with individuals in the general population. The disorder, characterized by an abnormal level of a plasma protein, requires lifelong monitoring as it is a pre-cancerous condition that can lead to multiple myeloma, a painful cancer of the plasma cells in the bone marrow. The study will appear in the June 18 issue of Blood, the official journal of the American Society of Hematology.

New Treatment Option At The Sarah Cannon Cancer Center Provides Hope For Inoperable Tumors

The Sarah Cannon Cancer Center (SCCC) at Centennial Medical Center last week began treating patients with a new non-invasive weapon in the battle against cancer. The Sarah Cannon Cancer Center is the first and only cancer center in Middle Tennessee to offer image-guided robotic stereotactic radiosurgery.

Nearly 9 In 10 Seniors Satisfied With Medigap

Medigap policyholders are overwhelmingly satisfied with their coverage and say it provides good value for their money, according to a new survey released today by the Blue Cross Blue Shield Association (BCBSA) and America"s Health Insurance Plans (AHIP).

Estrogens Do Not Protect Against Cardiovascular Death For Transsexuals

Long-term estrogen use does not protect male-to-female transsexuals from death due to cardiovascular disease but does not appear to raise their overall death rate, a new study found. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.

Doctors And Software Engineers Pioneer An Advanced Sepsis Detection And Management System

When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread.

Experts On Modeling Infectious Disease Spread

Scientists involved in the National Institutes of Health"s Models of Infectious Disease Agent Study (MIDAS) are developing computational tools to study the emergence, spread and containment of contagious outbreaks, including H1N1.

Hormone May Help Combat Frailty In Older Women

Frail elderly women with unexplained weight loss may benefit from supplementation with the body"s appetite-stimulating hormone, ghrelin, or with similar agents, according to a new study. Results of the study, which was funded partially by the National Institutes of Health, were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.

UK Tops The List Of 213 Countries At Extreme Risk To The Spread Of Swine Flu

A Warwick Business School professor and one of the founders of global risks specialist, Maplecroft, has released three new maps and indices revealing the countries most at risk from an influenza pandemic.

Alzheimer\'s Society Response To The Publication Of Revised NICE Guidance On Alzheimer\'s treatments

Thousands of people with Alzheimer"s will continue to be denied access to the only drug treatments for the disease following the publication of revised guidance by the NICE.

UK Authorities Confirm 101 Cases Swine Flu Human Infection

According to the Health Protection Agency (UK), another 14 patients who have been under investigation in England did have swine flu A (H1N1) infection, bringing the total number of confirmed cases throughout the United Kingdom to 101. The Health Protection Agency"s (HPA"s) laboratories carry out swine flu virus testing. The HPA announced that the new confirmed cases include 6 adults and 8 children in the East of England, London, and South East regions. 11 of the new cases had had contact with other people who were confirmed cases, while 2 had been abroad where the of the infection is still under investigation.

Dems Prepare For Health Reform Cost Analysis While Courting GOP Votes

What is sure to be a staggering price tag for health reform has Senate Democrats talking about changing the chamber"s normal accounting procedures, The Hill reports.

Obama Uses Popularity To Make Case For Health Reform In Wisconsin

President Obama used his popularity Thursday at a town hall meeting in Green Bay, Wisc., in an effort to help make the case to Americans that a health care system overhaul needs to happen this year, Time reports.

Genzyme Receives European Approval Of Renvela For Patients With Chronic Kidney Disease

Genzyme Corporation (Nasdaq: GENZ) announced that the European Commission has approved Renvela(R) (sevelamer carbonate) for the control of serum phosphorus in patients with chronic kidney disease (CKD). The approval includes patients not on dialysis with serum phosphorus levels greater than or equal to 1.78 mmol/L (5.5 mg/dL), and covers both the tablet and powder formulations.

Lawmakers Want Federal Rules To Cover Home Health Care Workers And End-Of-Life Care

Lawmakers want federal rules to cover home health care workers while Sen. Mark Warner, D-Va., plans to introduce legislation in Congress today to better educate the public on end-of-life care.

PCMA Statement On The Administration\'s Comments Regarding Financing Health Care Reform

The Pharmaceutical Care Management Association (PCMA) released the following statement today on the Administration"s comments regarding financing health care reform:

Global Post Articles Examine Malaria Worldwide

Global Post examines the quest for an effective vaccine to fight malaria. According to Global Post, "epidemiologists are pinning their hopes on a malaria vaccine" because "[k]illing mosquitoes, or avoiding bites, is an imprecise solution to malaria."

Recent Releases: HIV Prevention; Clinical Trials Debate; Definition Of Global Health; Drug Resistant TB

Future Studies Needed To Determine If "Test And Treat" Approach Could "End HIV Pandemic Within 50 Years," Researchers Say

Future Studies Needed To Determine If \'Test And Treat\' Approach Could \'End HIV Pandemic Within 50 Years,\' Researchers Say

In a Journal of the American Medical Association commentary piece, Anthony Fauci and Carl Dieffenbach of the National Institute of Allergy and Infectious Diseases explore results from a WHO mathematical model study that found universal, voluntary, annual HIV testing followed up with immediate treatment for those testing positive -- the "test and treat model" -- could "reduce HIV incidence" and "end the [HIV] pandemic within 50 years." Fauci said in a written statement, "Given these conclusions, test and treat potentially could represent an important public health strategy for fighting HIV/AIDS. However, the WHO model is based on numerous assumptions that need to be tested and also raises concerns about individual rights, cost effectiveness and other critical issues that require broad public debate" (NIAID release, 6/9). In their commentary, the authors highlight the various areas of research that are necessary to verify or refute the test and treat approach (Fauci/Dieffenbach, JAMA, 6/10).

L.A. County, Calif., Offers Home Delivery Of Chlamydia, Gonorrhea Test Kits

Los Angeles County health officials on Wednesday announced a program that will offer young women home delivery of chlamydia and gonorrhea testing kits and send them a text message when the results are available, the AP/San Francisco Chronicle reports. The $450,000 program aims to curb the rapid spread of sexually transmitted infections in the county while also reducing clinic wait times and costs.According to Centers for Disease Control and Prevention statistics, Los Angeles County in 2007 led the nation in reported chlamydia cases with 44,030 and ranked second for reported gonorrhea cases with 10,063. CDC has labeled chlamydia a hidden epidemic because women often display no symptoms. It is estimated that three million men and women contract the infection annually. Although chlamydia is treatable with antibiotics, women with untreated cases can experience infertility, higher risk for ectopic pregnancy and other problems. Peter Kerndt, director of the county"s STI program, said that the number of reported cases is expected to rise after the program"s implementation. According to county Health Director Jonathan Fielding, more than 50% of reported cases involve women younger than age 25, many of whom are black and Hispanic teens. It is recommended that women younger than age 25 receive annual testing.Under the program, 10,000 chlamydia and gonorrhea testing kits will be immediately available, with more offered as needed, according to county Supervisor Zev Yaroslavsky. To request a kit, women can visit a Web site or call a toll-free number to have the kits mailed to them. Women can administer the tests at home by inserting a vaginal swab for 10 seconds, sealing the swab in a plastic tube and mailing it to the testing center. They can opt to have a text message sent to their phone alerting them when their results are ready, which can be checked by phone or online. Women will then be referred to a local health clinic if needed. Similar programs have been implemented in Denver, Maryland, Washington, D.C., West Virginia and some Illinois counties. The Los Angeles County program is modeled on a Baltimore pilot program led by the Johns Hopkins School of Medicine (Mohajer, AP/San Francisco Chronicle, 6/11).

Sodium Channel Blocker Shows Promise As A Potential Treatment For Cystic Fibrosis

Cystic fibrosis patients may benefit from a new therapy that increases airway hydration, preventing the buildup of mucous, which is a key factor in the disease, according to researchers at Parion Sciences in Durham, N.C.

ANA Supports The Independence At Home Act

The American Nurses Association (ANA) applauds the efforts of lawmakers to bring primary care services offered through registered nurses to Medicare beneficiaries in their homes by reintroducing the "Independence at Home Act of 2009" (H.R. 2560/S. 1131). ANA supports this legislation because it provides patients with care options that enhance individual independence and can lead to a better quality of life. This legislation also smartly recognizes the integral role nurses and nurse practitioners play in the delivery of primary care and helps bring the focus of our health care system back where it belongs- on the patient and the community.

Advance In Understanding Cellulose Synthesis

Cellulose is a fibrous molecule that makes up plant cell walls, gives plants shape and form and is a target of renewable, plant-based biofuels research. But how it forms, and thus how it can be modified to design energy-rich crops, is not well understood. Now a study led by researchers at the Carnegie Institution"s Department of Plant Biology has discovered that the underlying protein network that provides the scaffolding for cell-wall structure is also the traffic cop for delivering the critical growth-promoting molecules where needed. The research, conducted in collaboration with colleagues at Wageningen University in the Netherlands and published in the advance online publication (AOP) of Nature Cell Biology on June 14th, is a significant step for understanding how the enzymes that make cellulose and determine plant cell shape arrive at the appropriate location in the cell to do their job.

Aussie And Kiwi Researchers Make Double MS Genetic Discovery

Australian and New Zealand researchers have accelerated research into Multiple Sclerosis by discovering two new locations of genes which will help to unravel the causes of MS and other autoimmune disease.

Young Adults Not Drinking Enough Milk

Calcium and dairy products play major roles in health maintenance and the prevention of chronic disease. Because peak bone mass is not achieved until the third decade of life, it is particularly important for young adults to consume adequate amounts of calcium, protein and vitamin D found in dairy products to support health and prevent osteoporosis later in life. In a study in the July/August issue of the Journal of Nutrition Education and Behavior, researchers report that young people actually reduce their intake of calcium and dairy products as they enter their twenties.

Positive Long-Term Data For BENLYSTA (formerly LYMPHOSTAT-B(R)) In Patients With Active Lupus

Human Genome Sciences (HGS) has reported continuation data from a Phase II study of BENLYSTA (belimumab, formerly LymphoStat-B) showing sustained improvement in patients with active systemic lupus after four years of treatment. The data was presented at the EULAR 2009 scientific meeting in Copenhagen, Denmark.

UCB And PatientsLikeMe Partner To Give People With Epilepsy A Voice In Advancing Research

Biopharma company UCB and PatientsLikeMe, the leading online community for people with life-changing conditions, today announced a strategic partnership to create an online, open epilepsy community that captures real-world experiences of people living with epilepsy in the U.S.

Making Waves: LSU\'s WAVCIS Increases Modeling Capabilities

LSU"s WAVCIS, or Wave-Current-Surge Information System for Coastal Louisiana, has a few new tricks up its sleeve in preparation for the 2009 hurricane season.

Robotic Ferret Will Detect Hidden Drugs And Weapons

A new type of robot being developed will make it easier to detect drugs, weapons, explosives and illegal immigrants concealed in cargo containers.

Personnel Concepts Readies A Workplace Preparedness Kit As WHO Proclaims H1N1 Flu Pandemic

As A/H1N1 flu cases in Europe and areas outside North America mounted, the World Health Organization (WHO) raised the global threat level to 6, proclaiming the world"s first flu pandemic in 41 years. Personnel Concepts was prepared.

Theratechnologies Presents Results From A Pharmacokinetic/Phamacodynamic Evaluation Of Tesamorelin At The Endocrine Society\'s Annual Meeting

Theratechnologies (TSX:TH) announced today that results from a pharmacokinetic/pharmacodynamic (PK/PD) evaluation of tesamorelin were presented as a poster (Poster number: P3-641) at the Endocrine Society"s 91st Annual Meeting in Washington D.C. Tesamorelin is an analogue of the growth hormone releasing factor evaluated for the treatment of excess abdominal fat in HIV patients with lipodystrophy.

What Are Gallstones? What Causes Gallstones?

Gallstones are lumps or stones that develop in the gallbladder or bile duct. Some of the chemicals which exist in the gallbladder, such as cholesterol, calcium bilirubinate, and calcium carbonate, harden into either one large stone or many small ones. According to Medilexicon"s medical dictionary, a gallstone is "A concretion in the gallbladder or a bile duct, composed chiefly of a mixture of cholesterol, calcium bilirubinate, and calcium carbonate, occasionally as a pure stone composed of just one of these substances". An article describes a gallbladder in the bile duct similar to trying to squeeze a golf ball through a straw.

Early Combination Of Enbrel(R) (etanercept) And Methotrexate Halts Radiographic Progression In 90% Of Patients During Second Year Of The COMET Study

New data presented this week during the European League Against Rheumatism (EULAR) Annual Meeting in Copenhagen demonstrated that sustained combination therapy (etanercept and methotrexate) was consistently superior to continuous methotrexate monotherapy in providing clinical remission and radiographic non-progression over two years in patients with early active rheumatoid arthritis.1 These new data add to the body of evidence supporting the benefits of early intervention with a biologic treatment in patients with rheumatoid arthritis.

U.S. House Of Representatives Sends Bill Granting The U.S. FDA Regulatory Control Over Tobacco Products To President Obama For Signature

Statement of Charles D. Connor, American Lung Association President and CEO:

Sinovac Completes Construction Of H1N1 Virus Seed Bank

Sinovac Biotech Ltd. (NYSE Amex: SVA), a leading developer and provider of vaccines in China, announced today that it has completed construction of the H1N1 virus seed bank necessary to produce a virus antigen.

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression In Rheumatoid Arthritis Models By Selective Inhibition Of The Immunoproteasome

Proteolix, Inc. announced that in an article published in Nature Medicine, Proteolix"s selective immunoproteasome inhibitor PR-957 was shown to block disease progression in mouse models of rheumatoid arthritis in a dose-dependent manner and to completely eliminate visible signs of disease at the highest dose. The anti-inflammatory effect induced by PR-957 was rapid and long-lasting, lowering expression of multiple inflammatory mediators, including TNF-a and IL-6. Disease regression was evident 24 hours after dosing and a complete amelioration of disease was achieved with a single dose. When compared to anti-TNF-a therapy (etanercept), PR-957 mediated a more rapid resolution of clinical symptoms, including joint inflammation, and was more effective than etanercept in a model of aggressive arthritis.

QLT Announces 12-month Results From Novartis Sponsored MONT BLANC Study Evaluating Standard-fluence Visudyne(R) Combination Therapy

QLT Inc. (NASDAQ: QLTI; TSX: QLT) announced that twelve-month primary analysis results from the Novartis sponsored Phase II MONT BLANC study were presented on June 14, 2009 during the 17th Congress of the European Society of Ophthalmology in Amsterdam, the Netherlands. MONT BLANC is the European study of the Novartis sponsored SUMMIT clinical trial program which investigates the efficacy and safety of combining Visudyne(R) (Novartis Pharma AG) and Lucentis(R) (Novartis Pharma AG, Genentech Inc.). SUMMIT also includes the DENALI study in the US and Canada and the EVEREST study in Asia. MONT BLANC is a 24-month randomized, double-masked, multicenter trial in patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration. The purpose of the study is to evaluate whether Visudyne combined with Lucentis is not inferior to Lucentis monotherapy with respect to the mean change from baseline in visual acuity (VA) and to evaluate the proportion of patients with a treatment-free interval of at least three months duration after Month 2. At the Month 12 examination, mean VA in the Visudyne combination therapy group improved 2.5 letters from baseline compared with a 4.4 letter improvement in the Lucentis monotherapy group. In the combination therapy group, 96% of patients had a three-month treatment-free interval, compared with 92% in the Lucentis monotherapy group.

Tumor Metabolism Discovery Opens New Detection And Treatment Options For Rare Form Of Colon Cancer

People who suffer from Peutz-Jeghers syndrome, a rare inherited cancer syndrome, develop gastrointestinal polyps and are predisposed to colon cancer and other tumor types. Carefully tracing the cellular chain-of-command that links nutrient intake to cell growth (and which is interrupted in Peutz-Jeghers syndrome), allowed researchers at the Salk Institute for Biological Studies to exploit the tumors" weak spot.

Tackling Dental Access Problem About More Than Numbers, Says BDA

Research published by consumer organisation Which? highlights the well-publicised problems some patients face accessing NHS dental care, according to the British Dental Association (BDA). The consumer organisation"s research indicates that, while nine out of ten people who tried to see an NHS dentist in the last two years were successful, three million people could not get an appointment.

FDA Warns Web Sites Against Marketing Fraudulent H1N1 Flu Virus Claims

The U.S. Food and Drug Administration is enforcing the laws that protect consumers from illegal products marketed through the Internet that claim to diagnose, prevent, mitigate, treat or cure the 2009 H1N1 flu virus.

Administration Could Find Compromise In Co-Op Plan

"With Republicans fighting the idea of a government-run health insurance plan, members of President Barack Obama"s team said Sunday that they are open to a compromise: a cooperative program that would expand coverage with taxpayer money but without direct governmental control," the Associated Press reports. The non-profit, health insurance cooperatives were suggested in Congress by Sen. Kent Conrad, D-N.D., and HHS Secretary Kathleen Sebelius said the concession could be a path to bipartisan health reform legislation (Elliott, 6/15).

Access Issues Persist For Indians, Rural Americans, Immigrants

Several reports today focus on inadequate health care for certain population groups within the United States.

Statements By Secretary Of Health And Human Services And Commissioner Of Food And Drugs, Regarding Passage Of The Family Smoking Prevention

Kathleen G. Sebelius: I am pleased Congress has taken swift action to pass the Family Smoking Prevention and Tobacco Control Act. The Food and Drug Administration (FDA) regulation of tobacco products will be a critical piece of a coordinated effort to save lives, lower costs and reduce suffering from heart disease, cancer and other tobacco-related illness. This is a great step towards a healthier America.

Summer Interns Arrive At Herman B Wells Center For Pediatric Research

Twenty-nine students arrived at Indiana University School of Medicine"s Herman B Wells Center for Pediatric Research to work a 10-week summer internship alongside top pediatric researchers. More than 250 applicants vied for the treasured research spots. Most of the candidates come from Indiana universities.

In Chronic Viral Infection Immune Exhaustion Driven By Antigen

One main reason why viruses such as HIV or hepatitis C persist despite a vigorous initial immune response is exhaustion. The T cells, or white blood cells, fighting a chronic infection eventually wear out.

Defeating Nicotine\'s Double Role In Lung Cancer

A lung cancer treatment that inhibits nicotine receptors was shown to double survival time in mice, according to Italian researchers.

Israeli Startup CLT Partners With Dutch Erasmus Medical Centre To Develop A Cure For Atrial Fibrillation

Today, the Israeli medtech startup company CLT Ltd. announced the establishment of Closed Loop Therapies (CLT) BV - a joint venture between Erasmus University Medical Centre (Rotterdam, the Netherlands), a highly prominent medical institute in Europe, and CLT Israel. The joint venture aims to develop and commercialise a novel therapeutic system, consisting of an arrhythmia-detecting drug pump combined with a unique drug, for automatic and immediate treatment of emerging atrial fibrillation (AF). Market size is estimated at 2.5-3 billion Euro, annually.

Pluristem Therapeutics Receives European Regulatory Approval For Placental-Derived Stem Cell Clinical Trial

Pluristem Therapeutics Inc. (NasdaqCM:PSTI) (DAX: PJT), a bio-therapeutics company dedicated to the commercialization of unrelated donor-patient (allogeneic) cell therapy products for a variety of disorders, announced today that the Paul Ehrlich Institute (PEI), the German competent authority in the European Union, has approved the Company"s Clinical Trial Application (CTA) and granted approval to begin clinical trials with its placental-derived adherent stromal cell product, termed PLX-PAD, for the treatment of critical limb ischemia (CLI), the end-stage of peripheral artery disease (PAD). In addition, Pluristem has already received approval from the Ethics Committee and, as previously announced, the US Food & Drug Administration (FDA) had cleared the Company"s Investigational New Drug (IND) application to initiate a similar trial in the United States. Both approvals of the CTA and IND clear the way for the world"s "first-in-man" clinical trial using PLX-PAD.

Stress Puts Double Whammy On Reproductive System, Fertility

University of California, Berkeley, researchers have found what they think is a critical and, until now, missing piece of the puzzle about how stress causes sexual dysfunction and infertility.

New Method Separates Cancer Cells From Normal Cells

The vast majority of cancer deaths are due to metastasis, the spread of cancer cells from its primary site to other parts of the body. These metastatic cells tend to move more than their non-metastatic variants but this movement is poorly understood. Scientists are studying cancer cells intently with the hope they can learn to control the movements of the dangerous cells.

ExonHit Announces Last Patient Out For EHT 0202 Phase IIa Study In Alzheimer\'s

ExonHit Therapeutics (Paris:ALEHT) announced that clinical testing of EHT 0202, its lead therapeutic compound in Alzheimer"s disease, is progressing well. Final patient dosing for the Phase IIa proof-of-concept clinical trial assessing EHT 0202 in patients with Alzheimer"s disease is completed.

Sleep Apnea Occurring During REM Sleep Is Significantly Associated With Type 2 Diabetes

A multi-ethnic study in the June 15 issue of the Journal of Clinical Sleep Medicine reports that there is a statistically significant relationship between obstructive sleep apnea (OSA) episodes occurring during rapid eye movement (REM) sleep and type 2 diabetes.

UPMC Cardiovascular Institute Recruiting For Severe Coronary Heart Disease Study

The UPMC Cardiovascular Institute currently is enrolling participants for a Phase 2 clinical trial to examine whether administering a naturally occurring protein improves blood supply to the cardiac muscle in patients with severe coronary artery disease.

Conference Invite: Unique Conference Specifically For Family Members Of OCD Sufferers, UK

OCD-UK is delighted to announce the first event of its kind, an OCD conference with a difference, a conference specifically aimed at the family, friends and carers of people with Obsessive-Compulsive Disorder (OCD).

Nearly One Half Of All Deaths On The Road Are Pedestrians, Cyclists And Motorcyclists, New WHO Study Reveals

The first global assessment of road safety finds that almost half of the estimated 1.27 million people who die in road traffic crashes each year are pedestrians, motorcyclists and cyclists. While progress has been made towards protecting people in cars, the needs of these vulnerable groups of road users are not being met.

Gene Evolution Process Discovered

One of the mechanisms governing how our physical features and behavioural traits have evolved over centuries has been discovered by researchers at the University of Leeds.

Mean New MicroRNA Data Analysis Method Gives Sharper Results

Our understanding of the importance of microRNAs in regulating gene expression is expanding, and with it our requirement for robust methods to measure their expression levels. Now a new method published in BioMed Central"s open access journal Genome Biology helps researchers to better understand the delicate interplay between differences in microRNA expression levels and their target genes.

Bacteria Are First Sensed By Cells Lining Blood Vessels, Not Immune Cells

Paul Kubes and colleagues, at the University of Calgary, Canada, have provided evidence in mice to refute the paradigm that the initial phase of the immune response to infection with Gram-negative bacteria (the recruitment of immune cells known as neutrophils to the site of infection) is triggered following immune sentinel-cell recognition of the bacterial molecule LPS via the protein TLR4. Rather, the researchers found that LPS recognition by TLR4 on the cells that line blood vessels (endothelial cells) is the crucial event that initiates neutrophil recruitment and bacterial clearance in mice.

Cambridge Consultants To Showcase Inhaler Design And Development Process At RDD 2009, Europe

Cambridge Consultants will be showcasing its proprietary design and development process for Dry Power Inhalers (DPIs) at the Respiratory Drug Delivery (RDD) Europe 2009 conference in Lisbon later this month.ч  The company will demonstrate its ability to move inhaler design quickly through all stages of development from concept through manufacture to final product, getting it right first time, accelerating the creation of new inhalable drug delivery devices, and offering pharmaceutical companies a quick route to market, saving up to six months in development.

The Downside Of Microtubule Stability - Study Shows Stalled Microtubules Might Be Responsible For Some Cases Of Charcot-Marie-Tooth Disease

Stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report in the June 15, 2009 issue of the Journal of Cell Biology. A mutant protein makes the microtubules too stable to perform their jobs, the researchers find.

Mapping Gene Expression With Gene Expression Atlas

Recently, researchers at the European Molecular Biology Laboratory"s European Bioinformatics Institute (EMBL-EBI) launched a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how gene expression varies in different cell types, tissues and under disease conditions can help researchers understand gene function and to develop new drugs and therapies.

UCSF And Abbott Launch Viral Discovery Center At Mission Bay

The University of California, San Francisco, has partnered with Abbott, a global health care company, to launch a first-of-its kind, non-profit viral diagnostics center near the UCSF Mission Bay campus to help identify unknown viruses from around the world.

MUHC Researcher Awarded $500,000 To Study Pathogenesis Of Infectious Disease

The Burroughs Wellcome Fund (BWF) has announced the recipients of the 2009 Investigators in the Pathogenesis of Infectious Disease Award. MUHC researcher Dr. Maya Saleh was one of six recipients granted $500,000 over a 6-year period for her research proposal, "Regulation and molecular mechanisms of NLR-mediated innate immunity."

Temple Podiatry Receives NIH Grant To Develop Personalized, Visual Diabetes Education Program

Loss of feeling in the feet is a common complication of diabetes, so it"s critical that those with the disease wear shoes that fit properly and check their feet often for cuts or sores. Left untreated, a diabetic"s foot wound can lead to a serious infection or even require amputation.

New Center Of Excellence Targets Reducing Disparities In Cancer Care And Outcomes

The University of South Florida and Moffitt Cancer Center have been awarded a highly competitive, $6-million federal grant to create a National Center on Minority Health and Health Disparities (NCMHD) Center of Excellence. The five-year program grant from the NCMHD, National Institutes of Health, will focus on research, education and training, and community outreach activities to reduce cancer-related health disparities among minority and underserved communities in Florida.

Sepracor Pharmaceuticals Ltd Withdraws Its Marketing Authorisation Application For Lunivia (eszopiclone)

The European Medicines Agency has been formally notified by Sepracor Pharmaceuticals Ltd of its decision to withdraw its application for a centralised marketing authorisation for the medicine Lunivia (eszopiclone), 2 and 3 mg tablets.

CRi Oosight(TM) Instrument Crucial In IVF Breakthrough Demonstrating A Correlation Between Non-Invasive Egg Metrics And Pregnancy

Cambridge Research & Instrumentation, Inc. (CRi) announced that Oosight(TM), a non-invasive optical imaging system manufactured by CRi and widely used by embryologists as an aid in the field of in vitro fertilization (IVF), has been used in a groundbreaking study that investigated ways to select eggs most likely to produce a pregnancy.

Sebelius: Single-Payer Health Care Not In Plans

In an interview with NPR, Health and Human Services Secretary Kathleen Sebelius stressed that talk of a public plan doesn"t mean that a single-payer option is a possibility. "This is not a trick. This is not single payerтЂ¦ That"s not what anyone is talking about - mostly because the president feels strongly, as I do, that dismantling private health coverage for the 180 million Americans that have it, discouraging more employers from coming into the marketplace, is really the bad, you know, is a bad direction to go," she said. Sebelius added that a public insurance option would pressure private insurance companies to lower costs, which she says is "a good thing for the American public. Medicare right now has lower overhead than private insurers." Some Republicans have argued that Americans currently in private plans would flee to the public option, but Sebelius countered that expanding health insurance would potentially create "50 million-plus new insurance customers, whether you"re talking about a private plan or public option."

Parents Ask Lawmakers To Keep Kids In Mind During Reform Debate

A group of 50 families will ask lawmakers this week to keep in mind 9 million uninsured children and many more who are underinsured when they undertake health reform this summer, the Cincinnati Enquirer reports. "Covering all children, and making sure they have access to the care they need regardless of their family"s financial situation or where they live, is an achievable first step toward covering all Americans," the CEO of the Children"s Hospital Association told the Enquirer.

California Budget Committee Votes To Reduce Proposed Cuts To HIV/AIDS Programs

A joint legislative budget committee in California on Monday rejected a number of Gov. Arnold Schwarzenegger"s (R) proposals to cut funding from some state programs to address the state"s $24.3 billion deficit, including a plan to cut $80.1 million from HIV/AIDS programs, the Sacramento Bee reports (Wiegand/Sanders, Sacramento Bee, 6/14). The committee voted to reduce the $80.1 million proposal, which would affect a number of HIV/AIDS education, prevention and treatment services, by roughly $50 million, to $33.5 million, according to the Los Angeles Times (Goldmacher, Los Angeles Times, 6/15).

Delaware State Senate Passes Bill Aimed At Reducing Mother-To-Child HIV Transmission

The Delaware State Senate recently passed a bill (SB 86) that would add HIV testing to the standard battery of tests given to all pregnant women, WMTD.com reports. Lawmakers hope that the bill will help reduce the rate of mother-to-child HIV transmission. Women would be able to choose to "opt out" of taking the test, according to WMTD.com (Saki, WMTD.com, 6/14).

U.N. Secretary-General, WHO Director-General Appeal For Continued Investment In Global Health

Despite the current global economic crisis, U.N. Secretary-General Ban Ki-moon on Monday called for a continued international commitment to investing in health, Xinhua/People"s Daily reports. "We can cut back on health expenditures and incur massive losses in lives and fundamental capacity for growth. Or we can invest in health and spare both people and economies the high cost of inaction," Ban said during an address at the U.N. Forum on Advancing Global Health in the Face of Crises, a day-long forum at U.N. headquarters in New York. "The cost of cutting back is just unthinkable" (Xinhua/People"s Daily, 6/16).

6 \'Major Health Agencies\' Form Alliance To Address Chronic Diseases In Developing Countries

A group of "major health agencies" from Australia, Canada, China, the U.K. and the U.S., which "together control 80 percent of the world"s public health-research funding," have joined together to form the Global Alliance for Chronic Diseases (GACD) to combat chronic diseases in developing countries, Time reports (Walsh, Time, 6/16).

UNICEF Highlights Child Survival On The Day Of The African Child

Several African countries have made impressive gains in child survival in recent years but much more needs to be done, UNICEF said today in marking the International Day of the African Child. This year"s theme is "Africa Fit for Children: A Call for Accelerated Action Towards Child Survival".

Hatwig Receives American Society of Health-System Pharmacists Award Of Excellence

The American Society of Health-System Pharmacists (ASHP) today honored Christopher A. Hatwig, M.S., FASHP, with the ASHP Board of Directors Award of Excellence for his work to help safety net hospitals provide safe and cost-effective drug therapy to low-income and uninsured patients. Hatwig, vice president of Apexus in Irving, Texas, received the award during ASHP"s Summer Meeting in Rosemont, Ill.

General Opitcal Council Consults On 2010-2015 Strategy, UK

The General Optical Council (GOC) has launched an open consultation on its five-year strategy. Registrants, patients and the public, and partner organisations are encouraged to have their say on the GOC"s role and work priorities for 2010-2015.

Agreements Secured For Pre-Pandemic Vaccine For The UK

Agreements have been signed between the UK Government and vaccine manufacturers to secure supplies of up to 90 million doses of pre-pandemic H1N1 vaccine before a pandemic begins, the Department of Health announced today.

Less Invasive CT-Scan Based Colorectal Cancer Screening Method Shows Good Accuracy

Computed tomographic (CT) colonography may offer patients at increased risk of colorectal cancer an alternative to colonoscopy that is less-invasive, is better-tolerated and has good diagnostic accuracy, according to a study in the June 17 issue of JAMA.

Therapy Helps Improve Outcomes For Patients With Severe Sepsis

A preliminary study suggests that a therapy for severe sepsis or septic shock that included the use of an antibiotic-based "hemoperfusion" device to remove toxic products of bacteria from the blood in addition to conventional treatment resulted in a reduced risk of death and appeared to improve blood circulation and reduce organ dysfunction, according to a report appearing in the June 17 issue of JAMA.

Trans Fats Hinder Multiple Steps In Blood Flow Regulation Pathways

Partially hydrogenated vegetable oils in processed foods contain trans fatty acids that interfere with the regulation of blood flow. A new report reveals a new way in which these "trans fats" gum up the cellular machinery that keeps blood moving through arteries and veins.

King Khalid University Hospital Links State-Of-The-Art Medical Imaging Applications With Aruba Networks\' 802.11n Solution From ASACO-IT

Aruba Networks, Inc. (NASDAQ: ARUN), a global leader in wireless LANs and secure mobility solutions, announced that Saudi Arabia"s King Khalid University Hospital (KKUH), the teaching hospital of King Saud University, has deployed Aruba"s high-speed 802.11n Wi-Fi and security solutions for PACS, RIS, and HIS applications at its facilities in Riyadh. KKUH is the largest teaching hospital in the Kingdom, with more than 800 beds and 500 medical specialists. The network was deployed by ASACO-IT (Ahd Al-Saudia Company), an authorized Aruba partner in Saudi Arabia.

Opioid-Induced Hibernation Protects Against Stroke

Using an opioid drug to induce a hibernatory state in rats reduces the damage caused by an artificial stroke. Researchers writing in the open access journal BMC Biology have shown that those animals put into the chemical fugue suffered less behavioral dysfunctions after a period of cerebral artery blockage than control rats.

Farmed Fish May Pose Risk For Mad Cow Disease

University of Louisville neurologist Robert P. Friedland, M.D., questions the safety of eating farmed fish in the June issue of the Journal of Alzheimer"s Disease, adding a new worry to concerns about the nation"s food supply.

CuraGen Announces Expansion Of CR011-vcMMAE Phase II Trial In Advanced Breast Cancer

CuraGen Corporation (Nasdaq: CRGN) announced that its Phase I/II Trial evaluating CR011-vcMMAE for the treatment of patients with advanced breast cancer has met the efficacy criteria for advancement to the second stage of enrollment. To date, 29 patients have been enrolled in this trial, including 15 in the Phase II portion. Two of the first four evaluable Phase II patients were progression-free at 12 weeks, therefore, as part of the Simon 2-Stage design, the Phase II trial will now advance to the second stage and enroll a total of approximately 25 patients. The principal investigator of the study is Dr. Linda Vahdat, Medical Director of the Breast Cancer Research Program and Associate Professor of Clinical Medicine, /Weill Cornell. CuraGen anticipates presenting updated results from this study during the second half of 2009.

Bicycle Helmet Laws For Kids Effective But Not Yet The Norm

Studies have shown wearing a helmet while riding a bicycle reduces one"s risk of death by more than 50 percent, yet every three days, a child in the United States is killed while riding a bicycle, and every day at least 100 children are treated in emergency rooms due to bicycle-related head injuries.

Protein In The Envelope Enclosing The Cell Nucleus A New Piece Of The Puzzle In Research On Cancer And Stem Cells?

A research team led by Professor Einar Hallberg at the Department of Life Sciences at Sз¶dertз¶rn University in Sweden has discovered a new protein in the inner membrane of the cell nucleus. This protein may play an important role in cell division and now provides a new piece of the puzzle to study in cancer research.

Vaccinating Children May Be Effective At Helping Control Spread Of Influenza

Targeting children may be an effective use of limited supplies of flu vaccine, according to research at the University of Warwick funded by the Wellcome Trust and the EU. The study suggests that, used to support other control measures, this could help control the spread of pandemics such as the current swine flu.

Brain Detects Happiness More Quickly Than Sadness

Our brains get a first impression of people"s overriding social signals after seeing their faces for only 100 milliseconds (0.1 seconds). Whether this impression is correct, however, is another question. Now an international group of experts has carried out an in-depth study into how we process emotional expressions, looking at the pattern of cerebral asymmetry in the perception of positive and negative facial signals.

Don\'t Forget Your Condoms At Swansea Pride, Says Terrence Higgins Trust Cymru

HIV and sexual health charity Terrence Higgins Trust (THT) Cymru is reminding visitors to Swansea Pride (Saturday 27th June) not to put their sexual health at risk by getting carried away with the party mood.

UN Secretary-General, World AIDS Campaign And UNAIDS Launch World AIDS Day Theme Of \'Universal Access And Human Rights\'

Ahead of this year"s World AIDS Day, the United Nations Secretary-General Ban Ki-moon, the World AIDS Campaign and the Joint United Nations Programme on HIV/AIDS (UNAIDS) have come together to announce the theme of "Universal Access and Human Rights".

Continued International Investment, Decreased Discrimination Key To Fight Against HIV/AIDS, Says U.N. Secretary-General

U.N. Secretary-General Ban Ki-Moon during a General Assembly meeting Tuesday urged governments not to cut aid for the international fight against HIV/AIDS, the AP/Washington Post reports. Even as Ban "called for "bold action" not only to increase funding but also to break down social barriers to achieve the goal set by world leaders in 2006 of universal access to comprehensive HIV prevention services, treatment, care and support by 2010," he and other speakers at the meeting "reviewing progress and challenges in the battle against AIDS indicated that it will be exceedingly difficult - if not impossible - to reach the goal" (Lederer, AP/Washington Post, 6/16).

Opinion: World Must Work Together To Stop Human Trafficking

"To some, human trafficking may seem like a problem limited to other parts of the world," Secretary of State Hillary Rodham Clinton writes in a Washington Post opinion piece, but "it occurs in every country, including the U.S., and we have a responsibility to fight it just as others do." According to Clinton, trafficking can produce "destructive effects" on "all of us," because it "weakens legitimate economies, breaks up families, fuels violence, threatens public health and safety, and shreds the social fabric that is necessary for progress." She writes that the problem is "particularly urgent now, as local economies around the world reel from the global financial crisis."

New Treatments Should Be Introduced Gradually To Avoid Later Problems, Says Expert

Concerns over whether the tests a treatment undergoes before release onto the market are enough to ensure its long-term safety are raised in an editorial published by BMJ Clinical Evidence today.

Many Floors In U. S. Homes Have "Measurable" Levels Of Pesticides

Insecticides used in and around homes - including products voluntarily removed from the market years ago - were measured on the floors of U.S. residences, according to the first study large enough to generate national data on pesticide residues in homes. It is scheduled for the June 15 issue of ACS" semi-monthly journal Environmental Science & Technology.

AARP: Shaheen-Collins Bill Will Keep Americans Healthier And Out Of The Hospital

AARP today proudly endorsed the bipartisan "Medicare

Study Supports Validity Of Test That Indicates Widespread Unconscious Bias

In the decade since the Implicit Association Test was introduced, its most surprising and controversial finding is its indication that about 70 percent of those who took a version of the test that measures racial attitudes have an unconscious, or implicit, preference for white people compared to blacks. This contrasts with figures generally under 20 percent for self report, or survey, measures of race bias.

\'Life Force\' Linked To Body\'s Ability To Withstand Stress

Our ability to withstand stress-related, inflammatory diseases may be associated, not just with our race and sex, but with our personality as well, according to a study published in the July issue of the journal Brain, Behavior and Immunity. Especially in aging women, low levels of the personality trait extraversion may signal that blood levels of a key inflammatory molecule have crossed over a threshold linked to a doubling of risk of death within five years.

Cytokinetics Announces The Initiation Of A First-Time-in-Humans, Phase I Clinical Trial Of CK-2017357

Cytokinetics, Incorporated (NASDAQ: CYTK) announced that the company has initiated a first-time-in-humans, Phase I clinical trial of CK-2017357 in healthy male volunteers. CK-2017357 is a fast skeletal muscle troponin activator and is the lead drug candidate that has emerged from the company"s skeletal sarcomere activator program. CK-2017357 selectively activates the troponin complex and increases its sensitivity to calcium, subsequently leading to an increase in skeletal muscle force. This mechanism of action has demonstrated encouraging pharmacological activity in preclinical models that may relate to the potential treatment of diseases associated with aging, muscle wasting, and neuromuscular dysfunction.